Stadium: Banterra Center
Home Manager: Bryan Mullins Away Manager: Dan Muller
| NCAAB | 2021/02/13 21:00 | Illinois St v Southern Illinois | W | 80-55 |
| NCAAB | 2020/01/25 20:00 | Southern Illinois v Illinois St | L | 58-55 |
| NCAAB | 2020/01/04 21:00 | Illinois St v Southern Illinois | L | 55-67 |
| NCAAB | 2019/03/02 19:00 | Illinois St v Southern Illinois | L | 63-72 |
| NCAAB | 2019/01/16 00:00 | Southern Illinois v Illinois St | W | 58-59 |
| NCAAB | 2018/03/04 00:10 | Illinois St v Southern Illinois | W | 76-68 |
| NCAAB | 2018/02/09 02:00 | Southern Illinois v Illinois St | W | 68-76 |
| NCAAB | 2018/01/13 23:00 | Illinois St v Southern Illinois | L | 70-74 |
| NCAAB | 2021/02/13 21:00 | Illinois St v Southern Illinois | W | 80-55 |
| NCAAB | 2021/02/07 20:00 | Missouri State v Illinois St | L | 72-62 |
| NCAAB | 2021/02/06 20:00 | Missouri State v Illinois St | L | 74-67 |
| NCAAB | 2021/02/02 00:00 | Illinois St v Drake | L | 60-95 |
| NCAAB | 2021/01/31 20:00 | Illinois St v Drake | L | 76-78 |
| NCAAB | 2021/01/24 23:00 | Valparaiso v Illinois St | L | 70-66 |
| NCAAB | 2021/01/23 23:00 | Valparaiso v Illinois St | L | 69-60 |
| NCAAB | 2021/01/21 02:00 | Bradley v Illinois St | W | 56-71 |
| NCAAB | 2021/02/13 21:00 | Illinois St v Southern Illinois | L | 80-55 |
| NCAAB | 2021/02/11 01:00 | Southern Illinois v Missouri State | L | 53-65 |
| NCAAB | 2021/02/07 21:00 | Southern Illinois v Bradley | W | 69-68 |
| NCAAB | 2021/02/06 21:00 | Southern Illinois v Bradley | L | 66-74 |
| NCAAB | 2021/01/31 23:00 | Northern Iowa v Southern Illinois | W | 68-71 |
| NCAAB | 2021/01/30 21:00 | Northern Iowa v Southern Illinois | L | 74-62 |
| NCAAB | 2021/01/26 22:00 | Southern Illinois v Indiana State | L | 59-71 |
| NCAAB | 2021/01/26 00:00 | Southern Illinois v Indiana State | L | 66-69 |