Head to Head
| Ghana Premier League | 2020/01/15 15:00 | Medeama SC v Asante Kotoko | W | 1-0 |
| Ghana Premier League | 2018/03/28 15:00 | Medeama SC v Asante Kotoko | W | 1-0 |
| Ghana FA Cup | 2017/10/02 15:00 | Asante Kotoko v Medeama SC | L | 1-0 |
| Ghana FA Cup | 2017/10/01 18:00 | Asante Kotoko v Medeama SC | D | 0-0 |
| Ghana Premier League | 2017/07/09 15:00 | Asante Kotoko v Medeama SC | L | 3-1 |
| Ghana Premier League | 2017/04/05 15:00 | Medeama SC v Asante Kotoko | W | 2-1 |
| Ghana Premier League | 2016/09/11 15:15 | Medeama SC v Asante Kotoko | D | 1-1 |
| Ghana Premier League | 2016/03/06 15:15 | Asante Kotoko v Medeama SC | D | 2-2 |
Home History
| Ghana Premier League | 2020/12/20 15:00 | Medeama SC v Liberty Professionals | D | 0-0 |
| Ghana Premier League | 2020/12/12 15:00 | Ebusua Dwarfs v Medeama SC | W | 0-1 |
| Ghana Premier League | 2020/11/27 18:00 | Legon Cities FC v Medeama SC | D | 0-0 |
| Ghana Premier League | 2020/11/22 15:00 | Dreams v Medeama SC | L | 2-1 |
| Ghana Premier League | 2020/11/15 15:00 | Medeama SC v Great Olympics | D | 1-1 |
| Ghana Premier League | 2020/03/14 19:00 | Legon Cities FC v Medeama SC | W | 0-2 |
| Ghana Premier League | 2020/03/11 15:00 | Medeama SC v Eleven Wonders | W | 2-0 |
| Ghana Premier League | 2020/03/07 15:00 | King Faisal v Medeama SC | D | 0-0 |
Away History
| CAF Champions League | 2020/12/23 15:00 | Asante Kotoko v Al Hilal Omdurman | L | 0-1 |
| Ghana Premier League | 2020/12/20 15:00 | Dreams v Asante Kotoko | W | 0-1 |
| Ghana Premier League | 2020/12/17 18:00 | Asante Kotoko v Great Olympics | L | 0-1 |
| Ghana Premier League | 2020/12/17 15:00 | Great Olympics v Asante Kotoko | L | 1-0 |
| Ghana Premier League | 2020/12/11 18:00 | Asante Kotoko v Legon Cities FC | W | 1-0 |
| CAF Champions League | 2020/12/06 15:00 | Asante Kotoko v FC Nouadhibou | W | 2-0 |
| CAF Champions League | 2020/11/29 16:00 | FC Nouadhibou v Asante Kotoko | D | 1-1 |
| Ghana Premier League | 2020/11/22 15:00 | Berekum Chelsea v Asante Kotoko | D | 1-1 |