[5] Clemson 34-10 Notre Dame [3] 2020-12-19 21:00
Stadium: Bank of America Stadium Round: 1
Head to Head
| NCAAF | 2020/11/08 00:30 | Clemson v Notre Dame | L | 40-47 |
| NCAAF | 2018/12/29 21:00 | Notre Dame v Clemson | W | 3-30 |
| NCAAF | 2015/10/04 00:00 | Clemson v Notre Dame | W | 24-22 |
Home History
| NCAAF | 2020/12/06 00:30 | Clemson v Virginia Tech | W | 45-10 |
| NCAAF | 2020/11/28 20:30 | Pittsburgh v Clemson | W | 17-52 |
| NCAAF | 2020/11/08 00:30 | Clemson v Notre Dame | L | 40-47 |
| NCAAF | 2020/10/31 16:00 | Boston College v Clemson | W | 28-34 |
| NCAAF | 2020/10/24 16:00 | Syracuse v Clemson | W | 21-47 |
| NCAAF | 2020/10/17 16:00 | Clemson v Georgia Tech | W | 73-7 |
| NCAAF | 2020/10/10 23:30 | Miami Florida v Clemson | W | 17-42 |
| NCAAF | 2020/10/04 00:00 | Virginia v Clemson | W | 23-41 |
Away History
| NCAAF | 2020/12/05 19:30 | Syracuse v Notre Dame | W | 21-45 |
| NCAAF | 2020/11/27 20:30 | Notre Dame v North Carolina | W | 31-17 |
| NCAAF | 2020/11/14 20:30 | Notre Dame v Boston College | W | 45-31 |
| NCAAF | 2020/11/08 00:30 | Clemson v Notre Dame | W | 40-47 |
| NCAAF | 2020/10/31 19:30 | Notre Dame v Georgia Tech | W | 31-13 |
| NCAAF | 2020/10/24 19:30 | Notre Dame v Pittsburgh | W | 45-3 |
| NCAAF | 2020/10/17 18:30 | Louisville v Notre Dame | W | 7-12 |
| NCAAF | 2020/10/10 23:30 | Florida State v Notre Dame | W | 26-42 |