Stadium: Fertitta Center
Home Manager: Kelvin Sampson Away Manager: Brian Gregory
| NCAAB | 2021/02/11 00:00 | Houston v South Florida | L | 82-65 |
| NCAAB | 2020/02/13 02:00 | Houston v South Florida | L | 62-58 |
| NCAAB | 2020/01/26 19:00 | South Florida v Houston | L | 49-68 |
| NCAAB | 2019/02/23 23:00 | South Florida v Houston | L | 59-71 |
| NCAAB | 2019/01/20 01:00 | Houston v South Florida | L | 69-60 |
| NCAAB | 2018/01/28 20:00 | South Florida v Houston | L | 40-63 |
| NCAAB | 2017/12/29 00:00 | Houston v South Florida | L | 79-60 |
| NCAAB | 2016/12/31 17:00 | Houston v South Florida | L | 70-56 |
| NCAAB | 2021/02/25 00:00 | Temple v South Florida | L | 65-47 |
| NCAAB | 2021/02/21 19:00 | South Florida v Temple | W | 83-76 |
| NCAAB | 2021/02/18 00:00 | South Florida v Central Florida | L | 65-81 |
| NCAAB | 2021/02/14 19:00 | Tulane v South Florida | L | 62-59 |
| NCAAB | 2021/02/11 00:00 | Houston v South Florida | L | 82-65 |
| NCAAB | 2021/01/09 18:00 | South Florida v East Carolina | W | 69-63 |
| NCAAB | 2021/01/06 21:00 | Tulsa v South Florida | L | 61-51 |
| NCAAB | 2021/01/03 00:00 | Central Florida v South Florida | W | 61-68 |
| NCAAB | 2021/02/26 00:00 | Western Kentucky v Houston | W | 57-81 |
| NCAAB | 2021/02/21 13:50 | Cincinnati v Houston | W | 52-90 |
| NCAAB | 2021/02/19 00:00 | Houston v Wichita State | L | 63-68 |
| NCAAB | 2021/02/11 00:00 | Houston v South Florida | W | 82-65 |
| NCAAB | 2021/02/06 20:00 | Houston v Our Lady Of The Lake | W | 112-46 |
| NCAAB | 2021/02/03 23:00 | Houston v East Carolina | L | 73-82 |
| NCAAB | 2021/01/31 18:00 | SMU v Houston | W | 48-70 |
| NCAAB | 2021/01/29 02:00 | Houston v Tulane | W | 83-60 |