Head to Head
| Ghana FA Cup | 2020/02/23 15:00 | Karela United FC v Medeama SC | L | 0-1 |
| Ghana Premier League | 2020/02/09 15:00 | Karela United FC v Medeama SC | D | 1-1 |
| World Club Friendlies | 2018/10/07 15:59 | Karela United FC v Medeama SC | L | 0-2 |
| Ghana Premier League | 2018/03/18 15:00 | Medeama SC v Karela United FC | L | 1-0 |
| World Club Friendlies | 2018/01/14 15:13 | Karela United FC v Medeama SC | D | 0-0 |
Home History
| Ghana Premier League | 2021/01/23 15:00 | Great Olympics v Karela United FC | D | 0-0 |
| Ghana Premier League | 2021/01/17 15:00 | Karela United FC v Berekum Chelsea | W | 4-1 |
| Ghana Premier League | 2021/01/10 15:00 | Eleven Wonders v Karela United FC | L | 3-1 |
| Ghana Premier League | 2021/01/03 15:00 | Karela United FC v Elmina Sharks | W | 3-1 |
| Ghana Premier League | 2020/12/18 15:00 | Bechem FC v Karela United FC | L | 2-1 |
| Ghana Premier League | 2020/12/13 15:00 | Karela United FC v King Faisal | W | 2-0 |
| Ghana Premier League | 2020/12/04 18:00 | Hearts of Oak v Karela United FC | D | 0-0 |
| Ghana Premier League | 2020/11/29 15:00 | Karela United FC v Dreams | W | 2-1 |
Away History
| Ghana Premier League | 2021/01/24 15:00 | Medeama SC v Inter Allies | W | 2-1 |
| Ghana Premier League | 2021/01/17 15:00 | Ashanti Gold v Medeama SC | D | 0-0 |
| Ghana Premier League | 2021/01/09 15:00 | Medeama SC v Aduana Stars | W | 2-1 |
| Ghana Premier League | 2021/01/03 15:00 | WAFA v Medeama SC | L | 5-4 |
| Ghana Premier League | 2020/12/27 15:00 | Medeama SC v Asante Kotoko | D | 1-1 |
| Ghana Premier League | 2020/12/20 15:00 | Medeama SC v Liberty Professionals | D | 0-0 |
| Ghana Premier League | 2020/12/12 15:00 | Ebusua Dwarfs v Medeama SC | W | 0-1 |
| Ghana Premier League | 2020/11/27 18:00 | Legon Cities FC v Medeama SC | D | 0-0 |