Head to Head
| Ghana Premier League | 2021/01/31 15:00 | Karela United FC v Medeama SC | L | 2-0 |
| Ghana FA Cup | 2020/02/23 15:00 | Karela United FC v Medeama SC | W | 0-1 |
| Ghana Premier League | 2020/02/09 15:00 | Karela United FC v Medeama SC | D | 1-1 |
| World Club Friendlies | 2018/10/07 15:59 | Karela United FC v Medeama SC | W | 0-2 |
| Ghana Premier League | 2018/03/18 15:00 | Medeama SC v Karela United FC | W | 1-0 |
| World Club Friendlies | 2018/01/14 15:13 | Karela United FC v Medeama SC | D | 0-0 |
Home History
| Ghana FA Cup | 2021/06/02 15:00 | Eleven Wise v Medeama SC | W | 0-1 |
| Ghana Premier League | 2021/05/30 15:00 | Inter Allies v Medeama SC | L | 3-0 |
| Ghana Premier League | 2021/05/23 15:00 | Medeama SC v Ashanti Gold | W | 1-0 |
| Ghana Premier League | 2021/05/16 15:00 | Aduana Stars v Medeama SC | L | 2-0 |
| Ghana Premier League | 2021/05/12 15:00 | Medeama SC v WAFA | L | 1-2 |
| Ghana Premier League | 2021/05/09 15:00 | Liberty Professionals v Medeama SC | D | 0-0 |
| Ghana Premier League | 2021/05/02 15:00 | Medeama SC v Ebusua Dwarfs | W | 3-0 |
| Ghana Premier League | 2021/04/24 15:00 | Asante Kotoko v Medeama SC | W | 1-2 |
Away History
| Ghana FA Cup | 2021/06/01 15:00 | Sekondi Hasaacas v Karela United FC | W | 3-5 |
| Ghana Premier League | 2021/05/28 15:00 | Karela United FC v Great Olympics | D | 1-1 |
| Ghana Premier League | 2021/05/23 15:00 | Berekum Chelsea v Karela United FC | D | 1-1 |
| Ghana Premier League | 2021/05/16 15:00 | Karela United FC v Eleven Wonders | W | 2-0 |
| Ghana Premier League | 2021/05/12 15:00 | Elmina Sharks v Karela United FC | D | 1-1 |
| Ghana Premier League | 2021/05/09 15:00 | Karela United FC v Bechem FC | W | 2-1 |
| Ghana Premier League | 2021/05/02 15:00 | King Faisal v Karela United FC | D | 1-1 |
| Ghana Premier League | 2021/04/25 15:00 | Karela United FC v Hearts of Oak | D | 1-1 |