Head to Head
| Ghana Premier League | 2021/02/04 15:00 | Medeama SC v Hearts of Oak | L | 1-0 |
| Ghana Premier League | 2020/01/05 15:00 | Medeama SC v Hearts of Oak | L | 3-0 |
| Ghana Premier League | 2018/06/03 15:00 | Hearts of Oak v Medeama SC | D | 1-1 |
| Ghana Premier League | 2017/10/15 15:00 | Medeama SC v Hearts of Oak | L | 1-0 |
| Ghana Premier League | 2017/02/19 15:00 | Hearts of Oak v Medeama SC | D | 0-0 |
| Ghana Premier League | 2016/09/14 15:00 | Hearts of Oak v Medeama SC | L | 0-1 |
| Ghana Premier League | 2016/02/28 15:15 | Medeama SC v Hearts of Oak | W | 0-2 |
| Ghana Premier League | 2015/08/16 15:00 | Medeama SC v Hearts of Oak | D | 0-0 |
Home History
| Ghana Premier League | 2021/06/06 18:00 | Great Olympics v Hearts of Oak | D | 1-1 |
| Ghana FA Cup | 2021/06/02 15:00 | Hearts of Oak v Liberty Professionals | W | 3-0 |
| Ghana Premier League | 2021/05/30 18:00 | Hearts of Oak v Berekum Chelsea | W | 2-0 |
| Ghana Premier League | 2021/05/21 15:00 | Eleven Wonders v Hearts of Oak | W | 0-1 |
| Ghana Premier League | 2021/05/16 18:00 | Hearts of Oak v Elmina Sharks | W | 2-0 |
| Ghana Premier League | 2021/05/12 15:00 | Bechem FC v Hearts of Oak | W | 0-1 |
| Ghana Premier League | 2021/05/09 18:00 | Hearts of Oak v King Faisal | W | 2-0 |
| Ghana Premier League | 2021/05/02 15:00 | Dreams v Hearts of Oak | L | 2-0 |
Away History
| Ghana Premier League | 2021/06/05 15:00 | Medeama SC v Karela United FC | W | 1-0 |
| Ghana FA Cup | 2021/06/02 15:00 | Eleven Wise v Medeama SC | W | 0-1 |
| Ghana Premier League | 2021/05/30 15:00 | Inter Allies v Medeama SC | L | 3-0 |
| Ghana Premier League | 2021/05/23 15:00 | Medeama SC v Ashanti Gold | W | 1-0 |
| Ghana Premier League | 2021/05/16 15:00 | Aduana Stars v Medeama SC | L | 2-0 |
| Ghana Premier League | 2021/05/12 15:00 | Medeama SC v WAFA | L | 1-2 |
| Ghana Premier League | 2021/05/09 15:00 | Liberty Professionals v Medeama SC | D | 0-0 |
| Ghana Premier League | 2021/05/02 15:00 | Medeama SC v Ebusua Dwarfs | W | 3-0 |