[3] Santos Laguna 1-1 Club America [8] 2021-02-01 01:06
Stadium: Estadio TSM Corona Round: 4
Referee: Diego Montano Robles Home Manager: Guillermo Almada Away Manager: Santiago Hernan Solari Poggio
Head to Head
| Mexico Liga MX | 2020/08/14 02:00 | Club America v Santos Laguna | L | 3-1 |
| Mexico Liga MX | 2019/11/03 01:00 | Club America v Santos Laguna | W | 1-2 |
| Mexico Liga MX | 2019/04/28 00:00 | Club America v Santos Laguna | L | 1-0 |
| World Club Friendlies | 2018/12/29 22:30 | Club America v Santos Laguna | D | 1-1 |
| Mexico Liga MX | 2018/11/12 00:00 | Santos Laguna v Club America | D | 1-1 |
| Mexico Liga MX | 2018/05/14 00:00 | Club America v Santos Laguna | D | 2-2 |
| Mexico Liga MX | 2018/05/11 00:30 | Santos Laguna v Club America | W | 4-1 |
| Mexico Liga MX | 2018/04/29 02:00 | Club America v Santos Laguna | L | 1-0 |
Home History
| Mexico Liga MX | 2021/01/23 03:30 | Mazatlan FC v Santos Laguna | D | 0-0 |
| Mexico Liga MX | 2021/01/18 01:06 | Santos Laguna v Tigres UANL | W | 2-0 |
| Mexico Liga MX | 2021/01/11 01:06 | Santos Laguna v Cruz Azul | W | 1-0 |
| Mexico Liga MX | 2020/11/22 01:00 | Santos Laguna v Pachuca | L | 0-3 |
| Mexico Liga MX | 2020/11/09 01:06 | Santos Laguna v Mazatlan FC | W | 4-0 |
| Mexico Liga MX | 2020/11/03 03:00 | Leon v Santos Laguna | L | 2-1 |
| Mexico Liga MX | 2020/10/26 01:06 | Santos Laguna v Atletico San Luis | W | 2-1 |
| Mexico Liga MX | 2020/10/19 00:06 | Santos Laguna v Pachuca | D | 1-1 |
Away History
| Mexico Liga MX | 2021/01/27 02:30 | Club America v Juarez FC | W | 2-0 |
| Mexico Liga MX | 2021/01/17 03:06 | Monterrey v Club America | L | 1-0 |
| Mexico Liga MX | 2021/01/10 03:00 | Club America v Atletico San Luis | W | 2-1 |
| CONCACAF Champions Cup | 2020/12/20 03:30 | Los Angeles FC v Club America | L | 3-1 |
| CONCACAF Champions Cup | 2020/12/17 01:00 | Atlanta United v Club America | L | 1-0 |
| Mexico Liga MX | 2020/11/29 03:06 | Club America v Chivas Guadalajara | L | 1-2 |
| Mexico Liga MX | 2020/11/26 03:06 | Chivas Guadalajara v Club America | L | 1-0 |
| Mexico Liga MX | 2020/11/07 03:30 | Juarez FC v Club America | D | 1-1 |