[4] Chivas Guadalajara Women 2-0 Santos Laguna Women [5] 2021-01-25 23:00
Stadium: Estadio Akron Round: 3
Head to Head
| Mexico Liga MX Femenil | 2020/09/15 00:00 | Santos Laguna Women v Chivas Guadalajara Women | D | 0-0 |
| Mexico Liga MX Femenil | 2020/02/11 03:00 | Santos Laguna Women v Chivas Guadalajara Women | D | 1-1 |
| Mexico Liga MX Femenil | 2019/10/13 17:00 | Chivas Guadalajara Women v Santos Laguna Women | L | 2-3 |
| Mexico Liga MX Femenil | 2019/03/12 03:00 | Santos Laguna Women v Chivas Guadalajara Women | L | 3-1 |
| Mexico Liga MX Femenil | 2019/01/22 03:00 | Chivas Guadalajara Women v Santos Laguna Women | D | 0-0 |
| Mexico Liga MX Femenil | 2018/10/02 02:00 | Santos Laguna Women v Chivas Guadalajara Women | W | 1-3 |
| Mexico Liga MX Femenil | 2018/07/29 17:30 | Chivas Guadalajara Women v Santos Laguna Women | W | 3-1 |
| Mexico Liga MX Femenil | 2018/03/25 18:30 | Chivas Guadalajara Women v Santos Laguna Women | L | 0-1 |
Home History
| Mexico Liga MX Femenil | 2021/01/16 16:00 | Mazatlan FC Women v Chivas Guadalajara Women | W | 1-2 |
| Mexico Liga MX Femenil | 2021/01/12 01:00 | Chivas Guadalajara Women v Juarez FC Women | W | 2-0 |
| Mexico Liga MX Femenil | 2020/11/30 23:00 | Chivas Guadalajara Women v Club America Women | D | 2-2 |
| Mexico Liga MX Femenil | 2020/11/27 18:00 | Club America Women v Chivas Guadalajara Women | L | 1-0 |
| Mexico Liga MX Femenil | 2020/11/21 00:00 | Tigres UANL Women v Chivas Guadalajara Women | L | 4-1 |
| Mexico Liga MX Femenil | 2020/11/17 01:00 | Chivas Guadalajara Women v Club America Women | L | 1-2 |
| Mexico Liga MX Femenil | 2020/11/08 18:00 | Puebla Women v Chivas Guadalajara Women | W | 0-5 |
| Mexico Liga MX Femenil | 2020/11/05 16:30 | Chivas Guadalajara Women v Tijuana Women | W | 3-0 |
Away History
| Mexico Liga MX Femenil | 2021/01/18 23:00 | Pachuca Women v Santos Laguna Women | W | 1-2 |
| Mexico Liga MX Femenil | 2021/01/12 01:00 | Santos Laguna Women v Puebla Women | W | 2-0 |
| Mexico Liga MX Femenil | 2020/11/20 01:00 | Santos Laguna Women v Toluca Women | W | 2-0 |
| Mexico Liga MX Femenil | 2020/11/14 15:00 | Cruz Azul Women v Santos Laguna Women | D | 0-0 |
| Mexico Liga MX Femenil | 2020/11/10 01:00 | Santos Laguna Women v Atletico San Luis Women | W | 2-1 |
| Mexico Liga MX Femenil | 2020/11/06 03:00 | Santos Laguna Women v Mazatlan FC Women | D | 1-1 |
| Mexico Liga MX Femenil | 2020/11/01 22:00 | Club Necaxa Women v Santos Laguna Women | W | 2-4 |
| Mexico Liga MX Femenil | 2020/10/19 17:00 | Queretaro Women v Santos Laguna Women | L | 2-1 |