Head to Head
| NHL | 2021/03/18 23:00 | BOS Bruins v BUF Sabres | L | 4-1 |
| NHL Pre-Season | 2020/03/09 12:42 | BOS Bruins v BUF Sabres | L | 3-2 |
| NHL | 2019/12/30 00:00 | BUF Sabres v BOS Bruins | L | 2-3 |
| NHL | 2019/12/28 00:00 | BOS Bruins v BUF Sabres | L | 3-0 |
| NHL | 2019/11/22 00:00 | BUF Sabres v BOS Bruins | L | 2-3 |
| NHL | 2019/01/06 00:00 | BUF Sabres v BOS Bruins | L | 1-2 |
| NHL | 2018/12/30 00:00 | BOS Bruins v BUF Sabres | L | 3-2 |
| NHL | 2018/12/16 22:00 | BUF Sabres v BOS Bruins | W | 4-2 |
Home History
| NHL | 2021/03/18 23:00 | BOS Bruins v BUF Sabres | L | 4-1 |
| NHL | 2021/03/16 23:00 | BUF Sabres v NJ Devils | L | 2-3 |
| NHL | 2021/03/15 23:00 | WAS Capitals v BUF Sabres | L | 6-0 |
| NHL | 2021/03/14 00:00 | PIT Penguins v BUF Sabres | L | 3-0 |
| NHL | 2021/03/12 00:00 | PIT Penguins v BUF Sabres | L | 5-2 |
| NHL | 2021/03/10 00:00 | BUF Sabres v PHI Flyers | L | 4-5 |
| NHL | 2021/03/07 17:00 | BUF Sabres v NY Islanders | L | 2-5 |
| NHL | 2021/03/06 18:00 | BUF Sabres v NY Islanders | L | 2-5 |
Away History
| NHL | 2021/03/18 23:00 | BOS Bruins v BUF Sabres | W | 4-1 |
| NHL | 2021/03/16 23:00 | BOS Bruins v PIT Penguins | W | 2-1 |
| NHL | 2021/03/15 23:00 | BOS Bruins v PIT Penguins | L | 1-4 |
| NHL | 2021/03/13 18:00 | NY Rangers v BOS Bruins | L | 4-0 |
| NHL | 2021/03/12 00:00 | NY Rangers v BOS Bruins | W | 0-4 |
| NHL | 2021/03/10 00:00 | BOS Bruins v NY Islanders | L | 1-2 |
| NHL | 2021/03/07 22:00 | NJ Devils v BOS Bruins | L | 1-0 |
| NHL | 2021/03/06 00:00 | WAS Capitals v BOS Bruins | W | 1-5 |