[22] Colchester 2-2 Tranmere [4] 2021-03-23 19:00
Stadium: JobServe Community Stadium Round: 22
Referee: Declan Bourne Home Manager: Wayne Brown Away Manager: Keith John Hill
Head to Head
| England League 2 | 2019/03/23 15:00 | Colchester v Tranmere | L | 0-2 |
| England League 2 | 2018/09/08 14:00 | Tranmere v Colchester | D | 1-1 |
Home History
| England League 2 | 2021/03/20 15:00 | Colchester v Port Vale | L | 0-1 |
| England League 2 | 2021/03/16 19:00 | Salford City v Colchester | D | 0-0 |
| England League 2 | 2021/03/13 17:30 | Grimsby v Colchester | D | 0-0 |
| England League 2 | 2021/03/09 19:00 | Harrogate Town v Colchester | L | 3-0 |
| England League 2 | 2021/03/06 15:00 | Colchester v Newport County | L | 0-2 |
| England League 2 | 2021/03/02 19:00 | Colchester v Carlisle | W | 2-1 |
| England League 2 | 2021/02/27 17:30 | Forest Green v Colchester | L | 3-0 |
| England League 2 | 2021/02/23 19:00 | Colchester v Exeter | L | 1-2 |
Away History
| England League 2 | 2021/03/20 15:00 | Tranmere v Exeter | W | 2-1 |
| England League 2 | 2021/03/17 19:00 | Grimsby v Tranmere | D | 0-0 |
| England EFL Trophy | 2021/03/14 15:00 | Sunderland v Tranmere | L | 1-0 |
| England League 2 | 2021/03/09 19:00 | Southend v Tranmere | W | 0-2 |
| England League 2 | 2021/03/06 15:00 | Tranmere v Crawley Town | L | 0-1 |
| England League 2 | 2021/03/02 19:00 | Tranmere v Newport County | W | 1-0 |
| England League 2 | 2021/02/27 15:00 | Leyton Orient v Tranmere | W | 1-3 |
| England League 2 | 2021/02/23 19:00 | Carlisle v Tranmere | W | 2-3 |