[21] Karen Khachanov 7-6,6-4 Mackenzie McDonald [120] 2021-03-10 15:10
Stadium: Central Round: 26 Ground: Hardcourt indoor
Home History
| ATP Rotterdam | 2021/03/05 12:00 | Karen Khachanov v Stefanos Tsitsipas | 6-4,3-6,5-7 |
| ATP Rotterdam | 2021/03/03 20:25 | Karen Khachanov v Cameron Norrie | 6-2,6-2 |
| ATP Rotterdam | 2021/03/02 13:30 | Stan Wawrinka v Karen Khachanov | 4-6,5-7 |
| Australian Open | 2021/02/13 06:10 | Karen Khachanov v Matteo Berrettini | 6-7,6-7,6-7 |
| Australian Open | 2021/02/11 02:00 | Karen Khachanov v Ricardas Berankis | 6-2,6-4,6-4 |
| Australian Open | 2021/02/09 02:25 | Karen Khachanov v Aleksandar Vukic | 6-3,6-7,7-6,6-4 |
| ATP Great Ocean Road Open | 2021/02/06 05:35 | Jannik Sinner v Karen Khachanov | 7-6,4-6,7-6 |
| ATP Great Ocean Road Open | 2021/02/05 06:30 | Botic Van De Zandschulp v Karen Khachanov | 7-6,5-7,3-6 |
Away History
| ATP Marseille | 2021/03/09 12:30 | Stefano Travaglia v Mackenzie McDonald | 6-7,6-7 |
| Challenger Nur-Sultan | 2021/03/04 07:35 | Mackenzie McDonald v Tomas Machac | 4-6,1-6 |
| Challenger Nur-Sultan | 2021/03/02 09:45 | Mackenzie McDonald v Brayden Schnur | 6-3,4-6,6-4 |
| Challenger Nur-Sultan | 2021/02/28 13:00 | Mackenzie McDonald v Jurij Rodionov | 6-1,6-2 |
| Challenger Nur-Sultan | 2021/02/27 05:00 | Mackenzie McDonald v Henri Laaksonen | 6-2,6-1 |
| Challenger Nur-Sultan | 2021/02/26 05:00 | Mackenzie McDonald v Frederico Ferreira Silva | 6-4,3-6,7-6 |
| Challenger Nur-Sultan | 2021/02/24 10:00 | Mackenzie McDonald v Denis Istomin | 6-2,6-3 |
| Challenger Nur-Sultan | 2021/02/22 13:00 | Mikhail Kukushkin v Mackenzie McDonald | 5-7,5-7 |