[185] Duke 70-56 Louisville [92] 2021-03-10 23:30
Stadium: Greensboro Coliseum Round: 124
Home Manager: Chris Mack Away Manager: Mike Krzyzewski
Head to Head
| NCAAB | 2021/02/27 23:00 | Louisville v Duke | L | 80-73 |
| NCAAB | 2021/01/23 21:00 | Duke v Louisville | L | 65-70 |
| NCAAB | 2020/01/18 23:00 | Louisville v Duke | L | 79-73 |
| NCAAB | 2019/02/13 02:00 | Duke v Louisville | W | 71-69 |
| NCAAB | 2018/02/22 02:00 | Louisville v Duke | W | 56-82 |
| NCAAB | 2017/03/09 19:30 | Duke v Louisville | W | 81-77 |
| NCAAB | 2017/01/14 17:00 | Duke v Louisville | L | 69-78 |
| NCAAB | 2016/02/20 17:00 | Louisville v Duke | L | 71-64 |
Home History
| NCAAB | 2021/03/09 21:30 | Boston College v Duke | W | 51-86 |
| NCAAB | 2021/03/06 23:00 | Duke v North Carolina | L | 73-91 |
| NCAAB | 2021/03/03 01:00 | Duke v Georgia Tech | L | 77-81 |
| NCAAB | 2021/02/27 23:00 | Louisville v Duke | L | 80-73 |
| NCAAB | 2021/02/23 00:00 | Syracuse v Duke | W | 71-85 |
| NCAAB | 2021/02/21 01:00 | Virginia v Duke | W | 65-66 |
| NCAAB | 2021/02/18 01:30 | Duke v Wake Forest | W | 84-60 |
| NCAAB | 2021/02/13 21:00 | Duke v NC State | W | 69-53 |
Away History
| NCAAB | 2021/03/06 21:00 | Virginia v Louisville | L | 68-58 |
| NCAAB | 2021/02/27 23:00 | Louisville v Duke | W | 80-73 |
| NCAAB | 2021/02/24 00:00 | Notre Dame v Louisville | W | 57-69 |
| NCAAB | 2021/02/20 23:00 | Louisville v North Carolina | L | 54-99 |
| NCAAB | 2021/02/01 19:00 | Georgia Tech v Louisville | W | 58-74 |
| NCAAB | 2021/01/28 02:00 | Louisville v Clemson | L | 50-54 |
| NCAAB | 2021/01/23 21:00 | Duke v Louisville | W | 65-70 |
| NCAAB | 2021/01/19 00:00 | Florida State v Louisville | L | 78-65 |