[5] Stefanos Tsitsipas 4-6,6-7 Alexander Zverev [7] 2021-03-21 03:00
Stadium: Estadio Arena GNP Seguros Round: 29 Ground: Hardcourt outdoor
Head to Head
| ATP Cup | 2020/01/05 09:30 | Alexander Zverev v Stefanos Tsitsipas | 1-6,4-6 |
| ATP World Tour Finals | 2019/11/13 20:00 | Stefanos Tsitsipas v Alexander Zverev | 6-3,6-2 |
| ATP Beijing | 2019/10/05 14:00 | Stefanos Tsitsipas v Alexander Zverev | 7-6,6-4 |
| ATP Madrid | 2019/05/10 17:30 | Stefanos Tsitsipas v Alexander Zverev | 7-5,3-6,6-2 |
| ATP Toronto | 2018/08/10 17:55 | Stefanos Tsitsipas v Alexander Zverev | 3-6,7-6,6-4 |
| ATP Washington | 2018/08/04 18:00 | Alexander Zverev v Stefanos Tsitsipas | 6-2,6-4 |
Home History
| ATP Acapulco | 2021/03/20 04:25 | Stefanos Tsitsipas v Lorenzo Musetti | 6-1,6-3 |
| ATP Acapulco | 2021/03/19 02:10 | Stefanos Tsitsipas v Felix Auger Aliassime | 7-5,4-6,6-3 |
| ATP Acapulco | 2021/03/18 04:00 | Stefanos Tsitsipas v John Isner | 6-3,6-2 |
| ATP Acapulco | 2021/03/17 02:40 | Stefanos Tsitsipas v Benoit Paire | 6-3,6-1 |
| ATP Marseille | 2021/03/12 17:00 | Pierre-Hugues Herbert v Stefanos Tsitsipas | 6-7,6-4,6-2 |
| ATP Marseille | 2021/03/11 17:55 | Lucas Pouille v Stefanos Tsitsipas | 2-6,3-6 |
| ATP Rotterdam | 2021/03/06 14:10 | Andrey Rublev v Stefanos Tsitsipas | 6-3,7-6 |
| ATP Rotterdam | 2021/03/05 12:00 | Karen Khachanov v Stefanos Tsitsipas | 6-4,3-6,5-7 |
Away History
| ATP Acapulco | 2021/03/20 02:00 | Dominik Koepfer v Alexander Zverev | 4-6,6-7 |
| ATP Acapulco | 2021/03/18 01:55 | Laslo Djere v Alexander Zverev | 4-6,3-6 |
| ATP Acapulco | 2021/03/16 02:00 | Carlos Alcaraz Garfia v Alexander Zverev | 3-6,1-6 |
| ATP Rotterdam | 2021/03/03 10:00 | Alexander Zverev v Alexander Bublik | 5-7,3-6 |
| Australian Open | 2021/02/16 09:45 | Novak Djokovic v Alexander Zverev | 6-7,6-2,6-4,7-6 |
| Australian Open | 2021/02/14 07:30 | Dusan Lajovic v Alexander Zverev | 4-6,6-7,3-6 |
| Australian Open | 2021/02/12 04:00 | Adrian Mannarino v Alexander Zverev | 3-6,3-6,1-6 |
| Australian Open | 2021/02/10 09:30 | Maxime Cressy v Alexander Zverev | 5-7,4-6,3-6 |