[13] Houston Dynamo 1-1 FC Cincinnati [22] 2021-07-04 00:30
Stadium: Shell Energy Stadium
Referee: Marcos De Oliveira Home Manager: Tabare Ramos Ricciard Away Manager: Jaap Stam
Home History
| USA MLS | 2021/06/27 00:00 | Real Salt Lake v Houston Dynamo | D | 1-1 |
| USA MLS | 2021/06/24 00:30 | Houston Dynamo v Portland Timbers | D | 2-2 |
| USA MLS | 2021/06/20 03:00 | Los Angeles FC v Houston Dynamo | D | 1-1 |
| USA MLS | 2021/05/30 00:30 | Sporting Kansas City v Houston Dynamo | L | 3-2 |
| USA MLS | 2021/05/23 01:00 | Houston Dynamo v Vancouver Whitecaps | W | 2-1 |
| USA MLS | 2021/05/16 01:00 | Colorado Rapids v Houston Dynamo | L | 3-1 |
| USA MLS | 2021/05/13 00:30 | Houston Dynamo v Sporting Kansas City | W | 1-0 |
| USA MLS | 2021/05/08 19:30 | FC Dallas v Houston Dynamo | D | 1-1 |
Away History
| USA MLS | 2021/06/26 23:00 | Toronto FC v FC Cincinnati | W | 0-2 |
| USA MLS | 2021/06/24 00:00 | Chicago Fire v FC Cincinnati | W | 0-1 |
| USA MLS | 2021/06/19 23:30 | FC Cincinnati v Colorado Rapids | L | 0-2 |
| USA MLS | 2021/05/29 19:00 | FC Cincinnati v New England Revolution | L | 0-1 |
| USA MLS | 2021/05/22 17:00 | CF Montreal v FC Cincinnati | W | 1-2 |
| USA MLS | 2021/05/16 20:00 | FC Cincinnati v Inter Miami CF | L | 2-3 |
| USA MLS | 2021/05/01 23:30 | Orlando City SC v FC Cincinnati | L | 3-0 |
| USA MLS | 2021/04/24 17:00 | New York City FC v FC Cincinnati | L | 5-0 |