[4] Libertad Asuncion 2-1 Guairena FC [3] 2021-04-12 00:30
Stadium: Estadio Dr. Nicolás Léoz Round: 11
Referee: Mario Alberto Diaz De Vivar Home Manager: Daniel Garnero Away Manager: Troadio Daniel Duarte
Head to Head
| Paraguay Division Profesional | 2021/02/24 22:00 | Guairena FC v Libertad Asuncion | L | 1-0 |
| Paraguay Division Profesional | 2020/10/17 23:15 | Guairena FC v Libertad Asuncion | W | 0-3 |
| Paraguay Division Profesional | 2020/09/05 21:30 | Libertad Asuncion v Guairena FC | W | 5-2 |
| Paraguay Division Profesional | 2020/02/28 23:00 | Guairena FC v Libertad Asuncion | L | 3-2 |
Home History
| Copa Libertadores Qualification | 2021/04/08 00:30 | Libertad Asuncion v Atletico Nacional Medellin | W | 1-0 |
| Paraguay Division Profesional | 2021/04/04 00:30 | Libertad Asuncion v Olimpia Asuncion | L | 0-1 |
| Paraguay Division Profesional | 2021/03/28 23:00 | Libertad Asuncion v Guarani Asuncion | D | 1-1 |
| Paraguay Division Profesional | 2021/03/22 23:30 | Libertad Asuncion v Sportivo Luqueno | W | 2-0 |
| Copa Libertadores Qualification | 2021/03/17 22:15 | Libertad Asuncion v Universidad Catolica del Ecuador | D | 2-2 |
| Paraguay Division Profesional | 2021/03/13 23:45 | Sol de America v Libertad Asuncion | W | 0-2 |
| Copa Libertadores Qualification | 2021/03/10 22:15 | Universidad Catolica del Ecuador v Libertad Asuncion | W | 0-1 |
| Paraguay Division Profesional | 2021/03/05 23:30 | 12 de Octubre v Libertad Asuncion | L | 2-1 |
Away History
| Copa Sudamericana | 2021/04/08 22:15 | River Plate Asuncion v Guairena FC | L | 4-2 |
| Paraguay Division Profesional | 2021/04/03 22:15 | Guairena FC v Sportivo Luqueno | W | 3-0 |
| Paraguay Division Profesional | 2021/03/22 21:15 | Guairena FC v Sol de America | D | 2-2 |
| Copa Sudamericana | 2021/03/18 22:15 | Guairena FC v River Plate Asuncion | L | 1-2 |
| Paraguay Division Profesional | 2021/03/14 20:45 | Guarani Asuncion v Guairena FC | W | 0-3 |
| Paraguay Division Profesional | 2021/03/09 21:30 | Guairena FC v 12 de Octubre | D | 0-0 |
| Paraguay Division Profesional | 2021/03/05 21:15 | River Plate Asuncion v Guairena FC | W | 0-1 |
| Paraguay Division Profesional | 2021/03/01 21:30 | Guairena FC v Nacional Asuncion | W | 1-0 |