[25] Inter Miami CF 3-2 Chicago Fire [20] 2021-08-18 23:30
Stadium: Chase Stadium
Referee: Baldomero Toledo Home Manager: Phil Neville Away Manager: Raphael Wicky
Home History
| USA MLS | 2021/08/15 00:00 | New York City FC v Inter Miami CF | L | 2-0 |
| USA MLS | 2021/08/08 22:00 | Inter Miami CF v Nashville SC | W | 2-1 |
| USA MLS | 2021/08/05 00:00 | Orlando City SC v Inter Miami CF | D | 1-1 |
| USA MLS | 2021/08/01 00:00 | Inter Miami CF v CF Montreal | W | 2-1 |
| USA MLS | 2021/07/25 23:30 | Inter Miami CF v Philadelphia Union | D | 1-1 |
| USA MLS | 2021/07/21 23:30 | Inter Miami CF v New England Revolution | L | 0-5 |
| USA MLS | 2021/07/03 23:30 | CF Montreal v Inter Miami CF | L | 1-0 |
| USA MLS | 2021/06/26 00:00 | Inter Miami CF v Orlando City SC | L | 1-2 |
Away History
| USA MLS | 2021/08/15 22:00 | Chicago Fire v Columbus Crew | W | 1-0 |
| USA MLS | 2021/08/08 22:00 | Chicago Fire v New York Red Bulls | W | 2-1 |
| USA MLS | 2021/08/05 00:00 | Chicago Fire v New York City FC | D | 0-0 |
| USA MLS | 2021/08/01 22:00 | Philadelphia Union v Chicago Fire | D | 1-1 |
| USA MLS | 2021/07/25 00:00 | Chicago Fire v Toronto FC | L | 1-2 |
| USA MLS | 2021/07/22 00:00 | Chicago Fire v DC United | D | 2-2 |
| USA MLS | 2021/07/18 00:30 | Nashville SC v Chicago Fire | L | 5-1 |
| USA MLS | 2021/07/08 00:00 | Chicago Fire v Orlando City SC | W | 3-1 |