[27] FC Cincinnati 3-4 Chicago Fire [23] 2021-10-20 23:30
Stadium: TQL Stadium
Referee: Jon Freemon Home Manager: Away Manager: Raphael Wicky
Head to Head
| USA MLS | 2021/06/24 00:00 | Chicago Fire v FC Cincinnati | W | 0-1 |
| USA MLS | 2020/09/02 23:30 | FC Cincinnati v Chicago Fire | D | 0-0 |
| USA MLS | 2020/08/25 23:30 | Chicago Fire v FC Cincinnati | L | 3-0 |
| USA MLS | 2019/09/21 23:30 | FC Cincinnati v Chicago Fire | D | 0-0 |
| USA MLS | 2019/07/14 00:00 | Chicago Fire v FC Cincinnati | W | 1-2 |
| World Club Friendlies | 2019/02/21 00:30 | FC Cincinnati v Chicago Fire | D | 1-1 |
| USA US Open Cup | 2017/06/29 00:00 | FC Cincinnati v Chicago Fire | W | 3-1 |
| Club Friendly List | 2017/02/22 21:00 | Chicago Fire v FC Cincinnati | L | 3-2 |
Home History
| USA MLS | 2021/10/16 23:30 | FC Cincinnati v Orlando City SC | L | 0-1 |
| USA MLS | 2021/10/10 00:00 | FC Cincinnati v Philadelphia Union | L | 1-2 |
| USA MLS | 2021/10/02 23:30 | FC Cincinnati v New York Red Bulls | L | 0-1 |
| USA MLS | 2021/09/29 23:00 | Toronto FC v FC Cincinnati | L | 3-2 |
| USA MLS | 2021/09/25 23:30 | DC United v FC Cincinnati | L | 4-2 |
| USA MLS | 2021/09/18 23:30 | FC Cincinnati v New York City FC | L | 1-2 |
| USA MLS | 2021/09/15 23:00 | Atlanta United v FC Cincinnati | L | 4-0 |
| USA MLS | 2021/09/12 00:00 | FC Cincinnati v Toronto FC | W | 2-0 |
Away History
| USA MLS | 2021/10/16 23:00 | New England Revolution v Chicago Fire | D | 2-2 |
| USA MLS | 2021/10/03 20:00 | Toronto FC v Chicago Fire | L | 3-1 |
| USA MLS | 2021/09/30 00:00 | Chicago Fire v New York City FC | W | 2-0 |
| USA MLS | 2021/09/26 17:00 | Chicago Fire v Nashville SC | D | 0-0 |
| USA MLS | 2021/09/23 00:00 | Chicago Fire v New England Revolution | L | 2-3 |
| USA MLS | 2021/09/19 17:00 | CF Montreal v Chicago Fire | L | 2-0 |
| USA MLS | 2021/09/15 23:30 | DC United v Chicago Fire | L | 3-0 |
| USA MLS | 2021/09/12 00:30 | Sporting Kansas City v Chicago Fire | L | 2-0 |