[3] Nacional De Football 4-4 Atletico Nacional Medellin [1] 2021-04-28 22:00
Stadium: Estadio Gran Parque Central Round: 2
Referee: Augusto Bergelio Aragon Bautista Home Manager: Away Manager: Alexandre Guimaraes
Home History
| Copa Libertadores | 2021/04/20 22:15 | Argentinos Jrs v Nacional De Football | L | 2-0 |
| Uruguay Grand Final | 2021/04/07 18:00 | Rentistas v Nacional De Football | W | 0-1 |
| Uruguay Grand Final | 2021/04/04 23:00 | Nacional De Football v Rentistas | W | 3-0 |
| Uruguay Clausura | 2021/03/28 23:00 | Deportivo Maldonado v Nacional De Football | W | 1-2 |
| Uruguay Clausura | 2021/03/25 00:15 | Nacional De Football v Boston River | L | 1-2 |
| Uruguay Clausura | 2021/03/22 00:15 | Nacional De Football v Liverpool Montevideo | L | 0-4 |
| Uruguay Clausura | 2021/03/13 19:30 | Danubio v Nacional De Football | L | 2-1 |
| Uruguay Clausura | 2021/03/08 00:45 | Nacional De Football v Defensor Sporting | W | 2-1 |
Away History
| Colombia Primera A | 2021/04/26 01:00 | La Equidad v Atletico Nacional Medellin | L | 1-0 |
| Copa Libertadores | 2021/04/23 00:00 | Atletico Nacional Medellin v Universidad Catolica | W | 2-0 |
| Colombia Primera A | 2021/04/18 20:30 | Atletico Nacional Medellin v Patriotas FC | W | 7-1 |
| Copa Libertadores Qualification | 2021/04/15 00:30 | Atletico Nacional Medellin v Libertad Asuncion | W | 4-1 |
| Colombia Primera A | 2021/04/11 01:00 | Deportivo Cali v Atletico Nacional Medellin | L | 1-0 |
| Copa Libertadores Qualification | 2021/04/08 00:30 | Libertad Asuncion v Atletico Nacional Medellin | L | 1-0 |
| Colombia Primera A | 2021/04/03 23:05 | Atletico Nacional Medellin v Envigado FC | W | 3-0 |
| Colombia Primera A | 2021/03/30 23:00 | Deportes Tolima v Atletico Nacional Medellin | L | 2-1 |