[3] Boca Juniors 0-0 Barcelona Guayaquil [1] 2021-05-21 00:00
Stadium: Alberto Jose Armando Round: 5
Referee: Wilmar Alexander Roldan Perez Home Manager: Miguel Angel Russo Away Manager: Fabian Bustos
Head to Head
| Copa Libertadores | 2021/05/05 00:30 | Barcelona Guayaquil v Boca Juniors | L | 1-0 |
Home History
| Argentina Copa de la Liga Profesional | 2021/05/16 20:30 | Boca Juniors v River Plate | W | 5-3 |
| Copa Libertadores | 2021/05/11 22:15 | Santos v Boca Juniors | L | 1-0 |
| Argentina Copa de la Liga Profesional | 2021/05/08 21:00 | Patronato Parana v Boca Juniors | L | 1-0 |
| Copa Libertadores | 2021/05/05 00:30 | Barcelona Guayaquil v Boca Juniors | L | 1-0 |
| Argentina Copa de la Liga Profesional | 2021/05/02 13:00 | Boca Juniors v Lanus | W | 1-0 |
| Copa Libertadores | 2021/04/28 00:30 | Boca Juniors v Santos | W | 2-0 |
| Argentina Copa de la Liga Profesional | 2021/04/24 21:00 | Huracan v Boca Juniors | W | 0-2 |
| Copa Libertadores | 2021/04/21 22:00 | The Strongest v Boca Juniors | W | 0-1 |
Away History
| Ecuador LigaPro Serie A | 2021/05/17 00:00 | Club 9 de Octubre v Barcelona Guayaquil | W | 0-1 |
| Copa Libertadores | 2021/05/11 22:15 | The Strongest v Barcelona Guayaquil | L | 2-0 |
| Copa Libertadores | 2021/05/05 00:30 | Barcelona Guayaquil v Boca Juniors | W | 1-0 |
| Ecuador LigaPro Serie A | 2021/05/02 01:30 | Barcelona Guayaquil v Delfin SC | W | 2-1 |
| Copa Libertadores | 2021/04/29 02:00 | Barcelona Guayaquil v The Strongest | W | 4-0 |
| Copa Libertadores | 2021/04/20 22:15 | Santos v Barcelona Guayaquil | W | 0-2 |
| Ecuador LigaPro Serie A | 2021/04/17 00:00 | Mushuc Runa v Barcelona Guayaquil | D | 2-2 |
| Ecuador LigaPro Serie A | 2021/04/12 22:00 | Barcelona Guayaquil v SD Aucas | W | 3-0 |