[7] Philadelphia Union 1-0 Nashville SC [5] 2021-10-23 23:30
Stadium: Subaru Park
Referee: Armando Villarreal Home Manager: Jim Curtin Away Manager: Gary Smith
Home History
| USA MLS | 2021/10/21 00:00 | Minnesota United v Philadelphia Union | L | 3-2 |
| USA MLS | 2021/10/16 17:00 | CF Montreal v Philadelphia Union | D | 2-2 |
| USA MLS | 2021/10/10 00:00 | FC Cincinnati v Philadelphia Union | W | 1-2 |
| USA MLS | 2021/10/03 20:00 | Philadelphia Union v Columbus Crew | W | 3-0 |
| USA MLS | 2021/09/29 23:30 | New York Red Bulls v Philadelphia Union | D | 1-1 |
| USA MLS | 2021/09/25 19:30 | Philadelphia Union v Atlanta United | W | 1-0 |
| USA MLS | 2021/09/19 20:00 | Philadelphia Union v Orlando City SC | W | 3-1 |
| CONCACAF Champions Cup | 2021/09/16 01:00 | Philadelphia Union v Club America | L | 0-2 |
Away History
| USA MLS | 2021/10/21 00:30 | Nashville SC v Columbus Crew | D | 1-1 |
| USA MLS | 2021/10/16 23:30 | DC United v Nashville SC | D | 0-0 |
| USA MLS | 2021/10/03 16:00 | New York City FC v Nashville SC | D | 0-0 |
| USA MLS | 2021/09/30 00:30 | Nashville SC v Orlando City SC | D | 2-2 |
| USA MLS | 2021/09/26 17:00 | Chicago Fire v Nashville SC | D | 0-0 |
| USA MLS | 2021/09/22 23:30 | Inter Miami CF v Nashville SC | W | 1-5 |
| USA MLS | 2021/09/18 23:30 | Toronto FC v Nashville SC | L | 2-1 |
| USA MLS | 2021/09/12 00:00 | CF Montreal v Nashville SC | W | 0-1 |