[5] Universidad Catolica 4-3 La Serena [8] 2021-08-08 00:00
Stadium: San Carlos de Apoquindo Round: 15
Referee: Christian Rojas Home Manager: Gustavo Augusto Pouyet Dominguez Away Manager: Miguel Ponce
Head to Head
| Chile Primera Division | 2021/02/05 20:00 | La Serena v Universidad Catolica | W | 1-2 |
| Chile Primera Division | 2020/11/01 21:30 | Universidad Catolica v La Serena | W | 3-0 |
| Chile Cup | 2019/07/10 00:00 | Universidad Catolica v La Serena | W | 8-6 |
| Chile Cup | 2019/06/09 00:00 | La Serena v Universidad Catolica | L | 1-0 |
Home History
| Chile Primera Division | 2021/08/01 20:00 | Universidad de Chile v Universidad Catolica | L | 2-1 |
| Chile Primera Division | 2021/07/29 16:30 | CD Antofagasta v Universidad Catolica | L | 3-2 |
| Chile Primera Division | 2021/07/26 00:00 | Universidad Catolica v O'Higgins | W | 3-0 |
| Copa Libertadores Qualification | 2021/07/21 22:15 | Palmeiras v Universidad Catolica | L | 1-0 |
| Chile Primera Division | 2021/07/17 20:00 | Universidad Catolica v Colo Colo | D | 0-0 |
| Copa Libertadores Qualification | 2021/07/14 22:15 | Universidad Catolica v Palmeiras | L | 0-1 |
| Chile Cup | 2021/07/03 19:00 | Universidad Catolica v Everton de Vina | L | 0-2 |
| Chile Cup | 2021/07/01 00:30 | Everton de Vina v Universidad Catolica | D | 0-0 |
Away History
| Chile Primera Division | 2021/08/02 18:30 | La Serena v CD Antofagasta | D | 1-1 |
| Chile Primera Division | 2021/07/25 16:30 | Huachipato v La Serena | D | 0-0 |
| Chile Primera Division | 2021/07/20 19:00 | La Serena v Palestino | W | 4-3 |
| Chile Cup | 2021/07/05 00:00 | Colo Colo v La Serena | L | 4-0 |
| Chile Cup | 2021/07/01 19:30 | La Serena v Colo Colo | L | 1-3 |
| Chile Cup | 2021/06/27 19:00 | La Serena v AC Colina | W | 5-0 |
| Chile Cup | 2021/06/23 19:30 | AC Colina v La Serena | W | 1-2 |
| Chile Primera Division | 2021/06/06 22:00 | Colo Colo v La Serena | L | 2-0 |