[12] Universidad de Chile 2-0 Melipilla [10] 2021-07-21 00:30
Stadium: Nacional Round: 11
Referee: Christian Rojas Home Manager: Rafael Dudamel Away Manager: John Sebastian Armijo
Home History
| Chile Cup | 2021/07/04 19:00 | CD Arturo Fernández Vial v Universidad de Chile | L | 6-5 |
| Chile Cup | 2021/07/02 00:30 | Universidad de Chile v CD Arturo Fernández Vial | D | 1-1 |
| Chile Cup | 2021/06/28 00:30 | San Luis Quillota v Universidad de Chile | W | 1-3 |
| Chile Cup | 2021/06/24 21:30 | Universidad de Chile v San Luis Quillota | W | 1-0 |
| Chile Primera Division | 2021/06/05 19:30 | Palestino v Universidad de Chile | D | 0-0 |
| Chile Primera Division | 2021/06/01 00:30 | Audax Italiano v Universidad de Chile | L | 2-1 |
| Chile Primera Division | 2021/05/24 00:30 | Universidad de Chile v Everton de Vina | L | 0-1 |
| Chile Primera Division | 2021/05/09 19:30 | CD Antofagasta v Universidad de Chile | W | 1-2 |
Away History
| Chile Cup | 2021/06/27 19:00 | Nublense v Melipilla | D | 0-0 |
| Chile Cup | 2021/06/23 19:30 | Melipilla v Nublense | L | 0-1 |
| Chile Primera Division | 2021/06/07 00:30 | Melipilla v O'Higgins | W | 3-1 |
| Chile Primera Division | 2021/05/29 19:00 | La Serena v Melipilla | L | 5-1 |
| Chile Primera Division | 2021/05/23 16:30 | Melipilla v CD Antofagasta | D | 1-1 |
| Chile Primera Division | 2021/05/08 22:00 | Santiago Wanderers v Melipilla | W | 0-3 |
| Chile Primera Division | 2021/05/02 22:00 | Melipilla v Universidad Catolica | W | 2-0 |
| Chile Primera Division | 2021/04/27 00:30 | Audax Italiano v Melipilla | L | 1-0 |