[82] Lorenzo Musetti 4-6,4-6 Reilly Opelka [47] 2021-05-11 11:10
Stadium: Court 1 Round: 25 Ground: Clay
Home History
| ATP Madrid | 2021/05/02 10:00 | Carlos Taberner v Lorenzo Musetti | 6-4,6-2 |
| ATP Madrid | 2021/05/01 09:00 | Lorenzo Musetti v Radu Albot | 6-3,6-4 |
| ATP Barcelona | 2021/04/21 09:00 | Lorenzo Musetti v Felix Auger Aliassime | 6-4,3-6,0-6 |
| ATP Barcelona | 2021/04/20 12:30 | Feliciano Lopez v Lorenzo Musetti | 4-6,3-6 |
| ATP Monte Carlo | 2021/04/12 09:00 | Lorenzo Musetti v Aslan Karatsev | 3-6,4-6 |
| ATP Cagliari | 2021/04/09 13:45 | Lorenzo Musetti v Laslo Djere | 4-6,6-4,2-6 |
| ATP Cagliari | 2021/04/08 10:50 | Daniel Evans v Lorenzo Musetti | 1-6,6-1,6-7 |
| ATP Cagliari | 2021/04/06 12:30 | Lorenzo Musetti v Dennis Novak | 6-0,6-1 |
Away History
| ATP Rome | 2021/05/09 13:30 | Richard Gasquet v Reilly Opelka | 1-6,5-7 |
| ATP Madrid | 2021/05/03 10:50 | Dominik Koepfer v Reilly Opelka | 6-4,6-4 |
| ATP Miami | 2021/03/26 15:00 | Alexei Popyrin v Reilly Opelka | 6-4,6-2 |
| ATP Dubai | 2021/03/14 10:00 | Kei Nishikori v Reilly Opelka | 3-6,6-3,6-4 |
| ATP Doha | 2021/03/08 16:30 | Reilly Opelka v Roberto Bautista-Agut | 6-4,3-6,4-6 |
| ATP Rotterdam | 2021/03/01 21:15 | Marton Fucsovics v Reilly Opelka | 7-6,6-7,7-6 |
| Australian Open | 2021/02/10 04:50 | Reilly Opelka v Taylor Fritz | 6-4,6-7,7-6,6-7,2-6 |
| Australian Open | 2021/02/08 00:00 | Reilly Opelka v Yen-Hsun Lu | 6-3,7-6,6-3 |