[2] Boca Juniors 5-3 River Plate [3] 2021-05-16 20:30
Stadium: Alberto Jose Armando Round: 3
Referee: Facundo Tello Figueroa Home Manager: Miguel Angel Russo Away Manager: Marcelo Gallardo
Head to Head
| Argentina Copa de la Liga Profesional | 2021/03/14 21:00 | Boca Juniors v River Plate | D | 1-1 |
| Argentina Copa de la Liga Profesional | 2021/01/03 00:30 | Boca Juniors v River Plate | D | 2-2 |
| Copa Libertadores Qualification | 2019/10/23 00:30 | Boca Juniors v River Plate | W | 1-0 |
| Copa Libertadores Qualification | 2019/10/02 00:30 | River Plate v Boca Juniors | L | 2-0 |
| Argentina Superliga | 2019/09/01 20:00 | River Plate v Boca Juniors | D | 0-0 |
| Copa Libertadores Qualification | 2018/12/09 19:30 | River Plate v Boca Juniors | L | 3-1 |
| Copa Libertadores Qualification | 2018/11/11 19:00 | Boca Juniors v River Plate | D | 2-2 |
| Argentina Superliga | 2018/09/23 20:45 | Boca Juniors v River Plate | L | 0-2 |
Home History
| Copa Libertadores | 2021/05/11 22:15 | Santos v Boca Juniors | L | 1-0 |
| Argentina Copa de la Liga Profesional | 2021/05/08 21:00 | Patronato Parana v Boca Juniors | L | 1-0 |
| Copa Libertadores | 2021/05/05 00:30 | Barcelona Guayaquil v Boca Juniors | L | 1-0 |
| Argentina Copa de la Liga Profesional | 2021/05/02 13:00 | Boca Juniors v Lanus | W | 1-0 |
| Copa Libertadores | 2021/04/28 00:30 | Boca Juniors v Santos | W | 2-0 |
| Argentina Copa de la Liga Profesional | 2021/04/24 21:00 | Huracan v Boca Juniors | W | 0-2 |
| Copa Libertadores | 2021/04/21 22:00 | The Strongest v Boca Juniors | W | 0-1 |
| Argentina Copa de la Liga Profesional | 2021/04/17 21:00 | Boca Juniors v Atlético Tucumán | W | 3-1 |
Away History
| Copa Libertadores | 2021/05/13 00:00 | Junior v River Plate | D | 1-1 |
| Argentina Copa de la Liga Profesional | 2021/05/09 17:30 | River Plate v CA Aldosivi | W | 4-1 |
| Copa Libertadores | 2021/05/07 00:00 | Independiente Santa Fe v River Plate | D | 0-0 |
| Argentina Copa de la Liga Profesional | 2021/05/02 19:30 | Banfield v River Plate | L | 1-0 |
| Copa Libertadores | 2021/04/29 00:00 | River Plate v Junior | W | 2-1 |
| Argentina Copa de la Liga Profesional | 2021/04/25 21:00 | River Plate v San Lorenzo | L | 1-2 |
| Copa Libertadores | 2021/04/22 22:00 | Fluminense v River Plate | D | 1-1 |
| Argentina Copa de la Liga Profesional | 2021/04/17 00:30 | Central Cordoba v River Plate | W | 0-5 |