[2] SF 49ers 17-11 PHI Eagles [9] 2021-09-19 17:00
Stadium: Lincoln Financial Field Round: 1
Home Manager: Nick Sirianni Away Manager: Kyle Shanahan
Head to Head
| NFL | 2020/10/05 00:20 | PHI Eagles v SF 49ers | L | 25-20 |
| NFL | 2017/10/29 17:00 | SF 49ers v PHI Eagles | L | 10-33 |
| NFL | 2014/09/28 20:25 | SF 49ers v PHI Eagles | W | 26-21 |
Home History
| NFL | 2021/09/12 17:00 | SF 49ers v DET Lions | W | 41-33 |
| NFL Preseason | 2021/08/29 20:00 | LV Raiders v SF 49ers | W | 10-34 |
| NFL Preseason | 2021/08/22 23:30 | SF 49ers v LA Chargers | W | 15-10 |
| NFL Preseason | 2021/08/15 00:30 | KC Chiefs v SF 49ers | L | 19-16 |
| NFL | 2021/01/03 21:25 | SEA Seahawks v SF 49ers | L | 26-23 |
| NFL | 2020/12/26 21:30 | SF 49ers v ARZ Cardinals | W | 20-12 |
| NFL | 2020/12/20 18:00 | SF 49ers v DAL Cowboys | L | 33-41 |
| NFL | 2020/12/13 21:25 | WAS Commanders v SF 49ers | L | 23-15 |
Away History
| NFL | 2021/09/12 17:00 | PHI Eagles v ATL Falcons | W | 32-6 |
| NFL Preseason | 2021/08/28 00:00 | PHI Eagles v NY Jets | D | 31-31 |
| NFL Preseason | 2021/08/19 23:30 | NE Patriots v PHI Eagles | L | 35-0 |
| NFL Preseason | 2021/08/12 23:30 | PIT Steelers v PHI Eagles | L | 24-16 |
| NFL | 2021/01/04 01:20 | WAS Commanders v PHI Eagles | L | 20-14 |
| NFL | 2020/12/27 21:25 | PHI Eagles v DAL Cowboys | L | 17-37 |
| NFL | 2020/12/20 21:05 | PHI Eagles v ARZ Cardinals | L | 26-33 |
| NFL | 2020/12/13 21:25 | NO Saints v PHI Eagles | W | 21-24 |