[3] ARZ Cardinals 12-30 DET Lions [32] 2021-12-19 18:00
Stadium: Ford Field Round: 1
Home Manager: Dan Campbell Away Manager: Kliff Kingsbury
Head to Head
| NFL | 2020/09/27 20:25 | DET Lions v ARZ Cardinals | L | 26-23 |
| NFL | 2019/09/08 20:25 | DET Lions v ARZ Cardinals | D | 27-27 |
| NFL | 2018/12/09 21:25 | DET Lions v ARZ Cardinals | L | 17-3 |
| NFL | 2017/09/10 17:00 | ARZ Cardinals v DET Lions | L | 23-35 |
| NFL | 2015/10/11 20:05 | DET Lions v ARZ Cardinals | W | 17-42 |
| NFL | 2014/11/16 21:25 | ARZ Cardinals v DET Lions | W | 14-6 |
Home History
| NFL | 2021/12/14 01:15 | LA Rams v ARZ Cardinals | L | 30-23 |
| NFL | 2021/12/05 18:00 | ARZ Cardinals v CHI Bears | W | 33-22 |
| NFL | 2021/11/21 21:25 | ARZ Cardinals v SEA Seahawks | W | 23-13 |
| NFL | 2021/11/14 21:05 | CAR Panthers v ARZ Cardinals | L | 34-10 |
| NFL | 2021/11/07 21:25 | ARZ Cardinals v SF 49ers | W | 31-17 |
| NFL | 2021/10/29 00:20 | GB Packers v ARZ Cardinals | L | 24-21 |
| NFL | 2021/10/24 20:25 | HOU Texans v ARZ Cardinals | W | 5-31 |
| NFL | 2021/10/17 20:05 | ARZ Cardinals v CLE Browns | W | 37-14 |
Away History
| NFL | 2021/12/12 21:05 | DET Lions v DEN Broncos | L | 10-38 |
| NFL | 2021/12/05 18:00 | MIN Vikings v DET Lions | W | 27-29 |
| NFL | 2021/11/25 17:30 | CHI Bears v DET Lions | L | 16-14 |
| NFL | 2021/11/21 18:00 | DET Lions v CLE Browns | L | 10-13 |
| NFL | 2021/11/14 18:00 | DET Lions v PIT Steelers | D | 16-16 |
| NFL | 2021/10/31 17:00 | PHI Eagles v DET Lions | L | 44-6 |
| NFL | 2021/10/24 20:05 | DET Lions v LA Rams | L | 19-28 |
| NFL | 2021/10/17 17:00 | CIN Bengals v DET Lions | L | 34-11 |