[12] BUF Bills 33-21 NE Patriots [8] 2021-12-26 18:00
Stadium: Gillette Stadium Round: 1
Home Manager: Bill Belichick Away Manager: Sean McDermott
Head to Head
| NFL | 2021/12/07 01:15 | NE Patriots v BUF Bills | L | 14-10 |
| NFL | 2020/12/29 01:15 | BUF Bills v NE Patriots | W | 38-9 |
| NFL | 2020/11/01 18:00 | NE Patriots v BUF Bills | W | 21-24 |
| NFL | 2019/12/21 21:30 | BUF Bills v NE Patriots | L | 17-24 |
| NFL | 2019/09/29 17:00 | NE Patriots v BUF Bills | L | 16-10 |
| NFL | 2018/12/23 18:00 | BUF Bills v NE Patriots | L | 12-24 |
| NFL | 2018/10/30 00:15 | NE Patriots v BUF Bills | L | 25-6 |
| NFL | 2017/12/24 18:00 | BUF Bills v NE Patriots | L | 16-37 |
Home History
| NFL | 2021/12/19 18:00 | CAR Panthers v BUF Bills | W | 14-31 |
| NFL | 2021/12/12 21:25 | BUF Bills v TB Buccaneers | L | 27-33 |
| NFL | 2021/12/07 01:15 | NE Patriots v BUF Bills | L | 14-10 |
| NFL | 2021/11/26 01:20 | BUF Bills v NO Saints | W | 31-6 |
| NFL | 2021/11/21 18:00 | IND Colts v BUF Bills | L | 41-15 |
| NFL | 2021/11/14 18:00 | BUF Bills v NY Jets | W | 45-17 |
| NFL | 2021/11/07 18:00 | BUF Bills v JAX Jaguars | L | 6-9 |
| NFL | 2021/10/31 17:00 | MIA Dolphins v BUF Bills | W | 11-26 |
Away History
| NFL | 2021/12/19 01:15 | NE Patriots v IND Colts | L | 17-27 |
| NFL | 2021/12/07 01:15 | NE Patriots v BUF Bills | W | 14-10 |
| NFL | 2021/11/28 18:00 | TEN Titans v NE Patriots | W | 13-36 |
| NFL | 2021/11/19 01:20 | NE Patriots v ATL Falcons | W | 25-0 |
| NFL | 2021/11/14 18:00 | CLE Browns v NE Patriots | W | 7-45 |
| NFL | 2021/11/07 18:00 | NE Patriots v CAR Panthers | W | 24-6 |
| NFL | 2021/10/31 20:05 | NE Patriots v LA Chargers | W | 27-24 |
| NFL | 2021/10/24 17:00 | NY Jets v NE Patriots | W | 13-54 |