[6] Club Deportes Santa Cruz 1-3 Deportes Iquique [13] 2021-05-30 16:00
Stadium: Estadio Municipal Joaquín Muñoz García Round: 8
Home History
| Chile Primera B | 2021/05/25 20:00 | Union San Felipe v Club Deportes Santa Cruz | L | 1-0 |
| Chile Primera B | 2021/05/19 00:30 | Club Deportes Santa Cruz v Coquimbo Unido | L | 1-7 |
| Chile Primera B | 2021/05/10 22:00 | Deportes Temuco v Club Deportes Santa Cruz | W | 0-1 |
| Chile Primera B | 2021/05/03 00:30 | Club Deportes Santa Cruz v Puerto Montt | W | 1-0 |
| Chile Primera B | 2021/04/26 19:30 | Santiago Morning v Club Deportes Santa Cruz | W | 1-3 |
| Chile Primera B | 2021/04/18 22:00 | Club Deportes Santa Cruz v Universidad de Concepcion | D | 2-2 |
| Chile Primera B | 2021/01/17 13:00 | Club Deportes Santa Cruz v Deportes Valdivia | W | 3-2 |
| Chile Primera B | 2021/01/12 21:00 | Magallanes v Club Deportes Santa Cruz | L | 2-0 |
Away History
| Chile Primera B | 2021/05/23 16:00 | Deportes Iquique v Magallanes | D | 1-1 |
| Chile Primera B | 2021/05/18 16:00 | Deportes Copiapo v Deportes Iquique | W | 0-2 |
| Chile Primera B | 2021/05/09 16:00 | Deportes Iquique v San Luis Quillota | D | 0-0 |
| Chile Primera B | 2021/05/03 16:00 | Barnechea v Deportes Iquique | L | 3-1 |
| Chile Primera B | 2021/04/25 16:00 | Deportes Iquique v San Marcos De Arica | L | 1-2 |
| Chile Primera B | 2021/04/04 15:00 | Deportes Iquique v Coquimbo Unido | L | 2-3 |
| Chile Primera Division | 2021/02/14 21:00 | Deportes Iquique v Santiago Wanderers | W | 2-0 |
| Chile Primera Division | 2021/02/11 21:30 | Audax Italiano v Deportes Iquique | D | 1-1 |