[12] Cobreloa 0-1 Club Deportes Santa Cruz [7] 2021-08-08 15:00
Stadium: Municipal de Calama Round: 14
Head to Head
| Chile Primera B | 2020/12/10 13:00 | Club Deportes Santa Cruz v Cobreloa | L | 4-1 |
| Chile Primera B | 2020/09/06 15:00 | Cobreloa v Club Deportes Santa Cruz | L | 0-1 |
| Chile Primera B | 2019/06/02 19:00 | Club Deportes Santa Cruz v Cobreloa | L | 1-0 |
Home History
| Chile Primera B | 2021/07/31 19:00 | Deportes Temuco v Cobreloa | L | 1-0 |
| Chile Primera B | 2021/07/21 15:00 | Cobreloa v Puerto Montt | W | 2-0 |
| Chile Primera B | 2021/07/14 22:00 | Deportes Copiapo v Cobreloa | D | 0-0 |
| Chile Primera B | 2021/07/09 19:30 | Cobreloa v Deportes Iquique | W | 3-2 |
| Chile Cup | 2021/06/27 16:00 | Cobreloa v O'Higgins | D | 8-8 |
| Chile Cup | 2021/06/23 21:30 | O'Higgins v Cobreloa | L | 1-0 |
| Chile Cup | 2021/06/15 19:00 | Cobreloa v Deportes Copiapo | W | 2-1 |
| Chile Primera B | 2021/06/07 16:30 | Magallanes v Cobreloa | D | 2-2 |
Away History
| Chile Primera B | 2021/08/03 18:00 | Barnechea v Club Deportes Santa Cruz | D | 0-0 |
| Chile Primera B | 2021/07/24 19:00 | Club Deportes Santa Cruz v CD Arturo Fernández Vial | L | 2-3 |
| Chile Primera B | 2021/07/21 19:30 | Club Deportes Santa Cruz v Magallanes | W | 2-0 |
| Chile Primera B | 2021/07/15 19:00 | Rangers de Talca v Club Deportes Santa Cruz | W | 1-3 |
| Chile Primera B | 2021/07/11 19:30 | Club Deportes Santa Cruz v San Luis Quillota | W | 2-0 |
| Chile Cup | 2021/06/26 22:00 | Club Deportes Santa Cruz v Everton de Vina | D | 1-1 |
| Chile Cup | 2021/06/24 00:00 | Everton de Vina v Club Deportes Santa Cruz | L | 3-0 |
| Chile Cup | 2021/06/15 19:00 | Colchagua CD v Club Deportes Santa Cruz | W | 1-6 |