[1] Cerezo Osaka 5-0 Guangzhou FC [4] 2021-07-06 10:00
Stadium: Chang Arena Round: 5
Referee: Bijan Heidari Home Manager: Levir Culpi Away Manager: Fabio Cannavaro
Head to Head
| AFC Champions League | 2021/06/24 10:00 | Guangzhou FC v Cerezo Osaka | W | 0-2 |
| AFC Champions League | 2018/04/17 11:00 | Guangzhou FC v Cerezo Osaka | L | 3-1 |
| AFC Champions League | 2018/02/21 10:00 | Cerezo Osaka v Guangzhou FC | D | 0-0 |
| AFC Champions League | 2014/05/13 12:00 | Guangzhou FC v Cerezo Osaka | W | 0-1 |
| AFC Champions League | 2014/05/06 10:00 | Cerezo Osaka v Guangzhou FC | L | 1-5 |
Home History
| AFC Champions League | 2021/07/03 10:00 | Port FC v Cerezo Osaka | W | 0-3 |
| AFC Champions League | 2021/06/30 10:00 | Port FC v Cerezo Osaka | D | 1-1 |
| AFC Champions League | 2021/06/27 14:00 | Cerezo Osaka v Kitchee | W | 2-1 |
| AFC Champions League | 2021/06/24 10:00 | Guangzhou FC v Cerezo Osaka | W | 0-2 |
| Japan Cup | 2021/06/09 09:00 | Cerezo Osaka v Gainare Tottori | W | 2-0 |
| Japan J-League | 2021/05/30 06:00 | Vegalta Sendai v Cerezo Osaka | D | 1-1 |
| Japan J-League | 2021/05/26 10:00 | Kashima Antlers v Cerezo Osaka | L | 1-0 |
| Japan J-League | 2021/05/23 06:00 | Cerezo Osaka v Sanfrecce Hiroshima | L | 1-2 |
Away History
| AFC Champions League | 2021/07/03 14:00 | Kitchee v Guangzhou FC | L | 1-0 |
| AFC Champions League | 2021/06/30 14:00 | Guangzhou FC v Kitchee | L | 0-1 |
| AFC Champions League | 2021/06/27 10:00 | Port FC v Guangzhou FC | L | 3-0 |
| AFC Champions League | 2021/06/24 10:00 | Guangzhou FC v Cerezo Osaka | L | 0-2 |
| China Super League | 2021/05/09 12:00 | Cangzhou Mighty Lions v Guangzhou FC | W | 0-2 |
| China Super League | 2021/05/02 12:00 | Guangzhou FC v ShenZhen | W | 2-0 |
| China Super League | 2021/04/27 07:35 | Shandong Taishan v Guangzhou FC | L | 1-0 |
| China Super League | 2021/04/20 12:00 | Guangzhou FC v Guangzhou City | D | 2-2 |