[8] Everton 3-1 Southampton [14] 2021-08-14 14:00
Stadium: Goodison Park Round: 1
Referee: Kevin Friend Home Manager: Rafael Benitez Maudes Away Manager: Ralph Hasenhuttl
Head to Head
| England Premier League | 2021/03/01 20:00 | Everton v Southampton | W | 1-0 |
| England Premier League | 2020/10/25 14:00 | Southampton v Everton | L | 2-0 |
| England Premier League | 2020/07/09 17:00 | Everton v Southampton | D | 1-1 |
| England Premier League | 2019/11/09 15:00 | Southampton v Everton | W | 1-2 |
| England Premier League | 2019/01/19 15:00 | Southampton v Everton | L | 2-1 |
| England EFL Cup | 2018/10/02 18:45 | Everton v Southampton | L | 4-5 |
| England Premier League | 2018/08/18 14:00 | Everton v Southampton | W | 2-1 |
| England Premier League | 2018/05/05 16:30 | Everton v Southampton | D | 1-1 |
Home History
| Elite Club Friendlies | 2021/08/07 11:45 | Man Utd v Everton | L | 4-0 |
| Elite Club Friendlies | 2021/07/28 22:00 | Everton v Unam Pumas | W | 1-0 |
| Elite Club Friendlies | 2021/07/25 22:00 | Everton v Millonarios | W | 11-10 |
| England Premier League | 2021/05/23 15:00 | Man City v Everton | L | 5-0 |
| England Premier League | 2021/05/19 17:00 | Everton v Wolverhampton | W | 1-0 |
| England Premier League | 2021/05/16 18:00 | Everton v Sheff Utd | L | 0-1 |
| England Premier League | 2021/05/13 17:00 | Aston Villa v Everton | D | 0-0 |
| England Premier League | 2021/05/09 15:30 | West Ham v Everton | W | 0-1 |
Away History
| Elite Club Friendlies | 2021/08/07 14:00 | Southampton v Athletic Bilbao | L | 1-3 |
| Elite Club Friendlies | 2021/08/04 18:00 | Southampton v Levante | W | 1-0 |
| Elite Club Friendlies | 2021/07/31 14:00 | Swansea v Southampton | W | 1-3 |
| Elite Club Friendlies | 2021/07/27 18:00 | Cardiff v Southampton | W | 0-4 |
| England Premier League | 2021/05/23 15:00 | West Ham v Southampton | L | 3-0 |
| England Premier League | 2021/05/18 17:00 | Southampton v Leeds | L | 0-2 |
| England Premier League | 2021/05/15 14:00 | Southampton v Fulham | W | 3-1 |
| England Premier League | 2021/05/11 19:15 | Southampton v Crystal Palace | W | 3-1 |