[16] Santos U20 1-3 Sao Paulo U20 [1] 2021-07-28 18:00
Stadium: Centro de Treinamento Rei Pele Round: 8
Head to Head
| Brazil Serie A U20 | 2020/11/22 19:00 | Santos U20 v Sao Paulo U20 | L | 1-5 |
| Brazil Serie A U20 | 2019/08/14 19:30 | Sao Paulo U20 v Santos U20 | L | 3-1 |
| Brazil Campeonato Paulista U20 | 2017/08/09 18:00 | Santos U20 v Sao Paulo U20 | D | 2-2 |
| Brazil Campeonato Paulista U20 | 2017/05/13 18:00 | Sao Paulo U20 v Santos U20 | L | 3-1 |
| Brazil Campeonato Paulista U20 | 2016/11/20 20:00 | Sao Paulo U20 v Santos U20 | L | 2-1 |
| Brazil Campeonato Paulista U20 | 2016/11/12 18:00 | Santos U20 v Sao Paulo U20 | D | 0-0 |
Home History
| Brazil Serie A U20 | 2021/07/25 19:00 | Atletico Paranaense U20 v Santos U20 | L | 3-2 |
| Brazil Serie A U20 | 2021/07/18 18:00 | Santos U20 v Fortaleza U20 | D | 0-0 |
| Brazil Serie A U20 | 2021/07/14 18:00 | Ceara U20 v Santos U20 | L | 2-1 |
| Brazil Serie A U20 | 2021/07/11 18:00 | Santos U20 v Chapecoense U20 | D | 1-1 |
| Brazil Serie A U20 | 2021/07/05 19:00 | Palmeiras U20 v Santos U20 | L | 2-1 |
| Brazil Serie A U20 | 2021/06/30 18:00 | Santos U20 v Gremio U20 | L | 2-5 |
| Brazil Serie A U20 | 2021/06/27 18:00 | Sport Recife U20 v Santos U20 | W | 0-1 |
| Brazil Serie A U20 | 2020/12/20 18:30 | Santos U20 v Goias U20 | W | 6-2 |
Away History
| Brazil Serie A U20 | 2021/07/25 18:00 | Sao Paulo U20 v Bahia U20 | W | 4-0 |
| Brazil Serie A U20 | 2021/07/18 13:00 | Vasco da Gama U20 v Sao Paulo U20 | W | 0-1 |
| Brazil Serie A U20 | 2021/07/14 18:00 | Sao Paulo U20 v Corinthians U20 | D | 1-1 |
| Brazil Serie A U20 | 2021/07/10 18:00 | Atletico Goianiense U20 v Sao Paulo U20 | W | 1-2 |
| Brazil Serie A U20 | 2021/07/04 18:00 | Sao Paulo U20 v Sport Recife U20 | W | 3-1 |
| Brazil Serie A U20 | 2021/06/30 18:00 | America MG U20 v Sao Paulo U20 | W | 1-3 |
| Brazil Serie A U20 | 2021/06/27 19:00 | Sao Paulo U20 v Atletico Paranaense U20 | W | 1-0 |
| Brazil Serie A U20 | 2021/01/03 19:00 | Atletico Paranaense U20 v Sao Paulo U20 | L | 1-0 |