[15] Newport County 2-2 Leyton Orient [6] 2021-09-04 14:00
Stadium: Rodney Parade Round: 6
Referee: Leigh Doughty Home Manager: Michael Flynn Away Manager: Kenneth Francis Jackett
Head to Head
| England League 2 | 2021/03/20 13:00 | Newport County v Leyton Orient | L | 0-1 |
| England League 2 | 2020/12/12 15:00 | Leyton Orient v Newport County | L | 2-1 |
| England FA Cup | 2020/11/07 15:00 | Leyton Orient v Newport County | W | 1-2 |
| England League 2 | 2020/01/25 15:00 | Leyton Orient v Newport County | L | 2-1 |
| England League 2 | 2019/12/29 15:00 | Newport County v Leyton Orient | D | 1-1 |
| England League 2 | 2017/03/04 15:00 | Newport County v Leyton Orient | L | 0-4 |
| England League 2 | 2016/08/13 14:00 | Leyton Orient v Newport County | W | 0-1 |
| England League 2 | 2016/01/26 19:45 | Leyton Orient v Newport County | L | 1-0 |
Home History
| England EFL Trophy | 2021/08/31 18:00 | Newport County v Plymouth | W | 2-0 |
| England League 2 | 2021/08/28 14:00 | Salford City v Newport County | L | 3-0 |
| England EFL Cup | 2021/08/25 18:45 | Newport County v Southampton | L | 0-8 |
| England League 2 | 2021/08/21 14:00 | Tranmere v Newport County | W | 0-1 |
| England League 2 | 2021/08/14 14:00 | Mansfield v Newport County | L | 2-1 |
| England EFL Cup | 2021/08/10 18:45 | Ipswich v Newport County | W | 0-1 |
| England League 2 | 2021/08/07 14:00 | Oldham v Newport County | W | 0-1 |
| World Club Friendlies | 2021/07/31 12:00 | Cardiff v Newport County | L | 2-0 |
Away History
| England League 2 | 2021/08/28 14:00 | Leyton Orient v Bradford | W | 2-0 |
| England League 2 | 2021/08/24 18:45 | Leyton Orient v Harrogate Town | L | 0-2 |
| England League 2 | 2021/08/21 14:00 | Carlisle v Leyton Orient | D | 1-1 |
| England League 2 | 2021/08/14 14:00 | Leyton Orient v Exeter | W | 3-0 |
| England EFL Cup | 2021/08/11 18:45 | Leyton Orient v QPR | L | 4-6 |
| England League 2 | 2021/08/07 14:00 | Salford City v Leyton Orient | D | 1-1 |
| Club Friendly List | 2021/07/31 13:00 | Leyton Orient v Gillingham | W | 2-0 |
| Club Friendly List | 2021/07/24 14:00 | Maidenhead Utd v Leyton Orient | W | 1-2 |