[4] Port Vale 3-0 Colchester [19] 2021-10-23 14:00
Stadium: Vale Park Round: 14
Referee: Sebastian Stockbridge Home Manager: Darrell Clarke Away Manager: Hayden Mullins
Head to Head
| England League 2 | 2021/03/20 15:00 | Colchester v Port Vale | W | 0-1 |
| England League 2 | 2020/12/12 15:00 | Port Vale v Colchester | D | 1-1 |
| England League 2 | 2020/02/15 15:00 | Port Vale v Colchester | W | 3-0 |
| England League 2 | 2019/08/03 14:00 | Colchester v Port Vale | D | 1-1 |
| England League 2 | 2019/01/12 15:00 | Port Vale v Colchester | L | 0-3 |
| England League 2 | 2018/08/11 14:00 | Colchester v Port Vale | L | 2-0 |
| England League 2 | 2018/01/27 15:00 | Port Vale v Colchester | D | 2-2 |
| England League 2 | 2017/12/23 15:00 | Colchester v Port Vale | D | 1-1 |
Home History
| England League 2 | 2021/10/19 18:45 | Mansfield v Port Vale | D | 1-1 |
| England League 2 | 2021/10/16 14:00 | Port Vale v Barrow | W | 3-1 |
| England League 2 | 2021/10/09 14:00 | Sutton Utd v Port Vale | L | 4-3 |
| England EFL Trophy | 2021/10/05 18:00 | Port Vale v Rochdale | W | 1-0 |
| England League 2 | 2021/10/02 14:00 | Port Vale v Leyton Orient | W | 3-2 |
| England League 2 | 2021/09/25 14:00 | Scunthorpe v Port Vale | W | 0-1 |
| England League 2 | 2021/09/18 14:00 | Port Vale v Harrogate Town | W | 2-0 |
| England League 2 | 2021/09/11 14:00 | Swindon v Port Vale | W | 1-2 |
Away History
| England League 2 | 2021/10/19 18:45 | Colchester v Bristol Rovers | D | 1-1 |
| England League 2 | 2021/10/16 14:00 | Colchester v Harrogate Town | W | 1-0 |
| England League 2 | 2021/10/08 18:45 | Tranmere v Colchester | L | 2-0 |
| England League 2 | 2021/10/02 14:00 | Colchester v Salford City | L | 0-2 |
| England EFL Trophy | 2021/09/28 18:30 | Colchester v West Ham U21 | W | 1-0 |
| England League 2 | 2021/09/25 14:00 | Swindon v Colchester | D | 0-0 |
| England League 2 | 2021/09/18 14:00 | Colchester v Crawley Town | L | 0-1 |
| England League 2 | 2021/09/10 18:45 | Barrow v Colchester | W | 2-3 |