[4] Tranmere 4-0 Scunthorpe [23] 2022-01-08 15:00
Stadium: Prenton Park Round: 26
Referee: Christopher Pollard Home Manager: Micky Mellon Away Manager: Keith John Hill
Head to Head
| England League 2 | 2021/08/28 14:00 | Scunthorpe v Tranmere | L | 1-0 |
| England League 2 | 2021/04/10 14:00 | Scunthorpe v Tranmere | D | 0-0 |
| England League 2 | 2020/10/03 14:00 | Tranmere v Scunthorpe | W | 2-0 |
Home History
| England League 2 | 2021/12/26 15:00 | Tranmere v Barrow | W | 2-0 |
| England EFL Trophy | 2021/12/21 19:00 | Tranmere v Harrogate Town | L | 1-2 |
| England League 2 | 2021/12/18 15:00 | Tranmere v Leyton Orient | W | 1-0 |
| England League 2 | 2021/12/11 15:00 | Exeter v Tranmere | W | 0-1 |
| England League 2 | 2021/12/07 19:45 | Oldham v Tranmere | W | 0-1 |
| England FA Cup | 2021/12/04 15:00 | Leyton Orient v Tranmere | L | 4-0 |
| England League 2 | 2021/11/23 19:45 | Tranmere v Bradford | W | 2-1 |
| England League 2 | 2021/11/20 15:00 | Bristol Rovers v Tranmere | D | 2-2 |
Away History
| England League 2 | 2022/01/01 15:00 | Scunthorpe v Carlisle | L | 0-1 |
| England League 2 | 2021/12/26 15:00 | Oldham v Scunthorpe | W | 1-3 |
| England League 2 | 2021/12/11 15:00 | Hartlepool v Scunthorpe | D | 0-0 |
| England League 2 | 2021/12/07 19:45 | Stevenage v Scunthorpe | D | 1-1 |
| England League 2 | 2021/11/27 15:00 | Scunthorpe v Bradford | D | 1-1 |
| England League 2 | 2021/11/23 19:45 | Scunthorpe v Leyton Orient | D | 1-1 |
| England League 2 | 2021/11/20 15:00 | Mansfield v Scunthorpe | L | 3-1 |
| England League 2 | 2021/11/13 15:00 | Scunthorpe v Salford City | D | 1-1 |