[9] Portsmouth 0-0 Sheff Wed [8] 2021-12-07 19:45
Stadium: Fratton Park Round: 21
Referee: Sam Purkiss Home Manager: Danny Cowley Away Manager: Darren Moore
Home History
| England FA Cup | 2021/12/04 15:00 | Portsmouth v Harrogate Town | L | 1-2 |
| England League 1 | 2021/11/27 15:00 | Gillingham v Portsmouth | W | 0-1 |
| England League 1 | 2021/11/23 19:45 | Lincoln City v Portsmouth | W | 0-3 |
| England League 1 | 2021/11/20 15:00 | Portsmouth v AFC Wimbledon | W | 2-1 |
| England League 1 | 2021/11/13 15:00 | Wycombe v Portsmouth | W | 0-1 |
| England EFL Trophy | 2021/11/09 19:45 | Portsmouth v Crystal Palace U21 | W | 3-0 |
| England FA Cup | 2021/11/06 15:00 | Portsmouth v Harrow Borough | W | 1-0 |
| England League 1 | 2021/11/02 19:45 | Portsmouth v Cheltenham | D | 1-1 |
Away History
| England EFL Trophy | 2021/12/01 19:00 | Sheff Wed v Hartlepool | L | 0-3 |
| England League 1 | 2021/11/27 15:00 | Sheff Wed v Wycombe | D | 2-2 |
| England League 1 | 2021/11/23 19:45 | Sheff Wed v Milton Keynes Dons | W | 2-1 |
| England League 1 | 2021/11/20 15:00 | Accrington Stanley v Sheff Wed | W | 2-3 |
| England FA Cup | 2021/11/16 19:45 | Plymouth v Sheff Wed | L | 3-0 |
| England League 1 | 2021/11/13 15:00 | Sheff Wed v Gillingham | D | 1-1 |
| England EFL Trophy | 2021/11/09 19:00 | Sheff Wed v Harrogate Town | W | 4-0 |
| England FA Cup | 2021/11/07 12:15 | Sheff Wed v Plymouth | D | 0-0 |