[8] Portsmouth 1-2 Milton Keynes Dons [5] 2022-01-15 15:00
Stadium: Fratton Park Round: 28
Referee: Scott Oldham Home Manager: Danny Cowley Away Manager: Liam Manning
Head to Head
| England League 1 | 2021/09/11 14:00 | Milton Keynes Dons v Portsmouth | L | 1-0 |
| England League 1 | 2021/04/17 11:30 | Milton Keynes Dons v Portsmouth | L | 1-0 |
| England League 1 | 2020/10/10 14:00 | Portsmouth v Milton Keynes Dons | W | 2-1 |
| England League 1 | 2020/02/25 19:45 | Portsmouth v Milton Keynes Dons | W | 3-1 |
| England League 1 | 2019/12/29 15:00 | Milton Keynes Dons v Portsmouth | L | 3-1 |
| England League 1 | 2018/02/10 15:00 | Milton Keynes Dons v Portsmouth | W | 1-2 |
| England League 1 | 2017/10/14 14:00 | Portsmouth v Milton Keynes Dons | W | 2-0 |
Home History
| England EFL Trophy | 2022/01/11 19:00 | Cambridge Utd v Portsmouth | L | 2-1 |
| England EFL Trophy | 2022/01/07 19:30 | Exeter v Portsmouth | W | 2-3 |
| England League 1 | 2022/01/03 15:00 | Cambridge Utd v Portsmouth | D | 0-0 |
| England League 1 | 2021/12/11 15:00 | Portsmouth v Morecambe | W | 2-0 |
| England League 1 | 2021/12/07 19:45 | Portsmouth v Sheff Wed | D | 0-0 |
| England FA Cup | 2021/12/04 15:00 | Portsmouth v Harrogate Town | L | 1-2 |
| England League 1 | 2021/11/27 15:00 | Gillingham v Portsmouth | W | 0-1 |
| England League 1 | 2021/11/23 19:45 | Lincoln City v Portsmouth | W | 0-3 |
Away History
| England League 1 | 2022/01/11 19:45 | Milton Keynes Dons v AFC Wimbledon | W | 1-0 |
| England League 1 | 2022/01/08 15:00 | Accrington Stanley v Milton Keynes Dons | D | 1-1 |
| England EFL Trophy | 2022/01/04 19:00 | Charlton v Milton Keynes Dons | L | 1-0 |
| England League 1 | 2022/01/01 15:00 | Milton Keynes Dons v Gillingham | D | 0-0 |
| England League 1 | 2021/12/26 15:00 | Lincoln City v Milton Keynes Dons | W | 2-3 |
| England League 1 | 2021/12/11 15:00 | Milton Keynes Dons v Oxford Utd | L | 1-2 |
| England League 1 | 2021/12/08 19:45 | Milton Keynes Dons v Plymouth | D | 1-1 |
| England EFL Trophy | 2021/11/30 19:00 | Leyton Orient v Milton Keynes Dons | W | 4-5 |