[9] TSG Hoffenheim 0-2 Mainz [7] 2021-09-11 13:30
Stadium: PreZero Arena Round: 4
Referee: Marco Fritz Home Manager: Sebastian Hoeness Away Manager: Bo Svensson
Head to Head
| Germany Bundesliga I | 2021/03/21 12:30 | TSG Hoffenheim v Mainz | L | 1-2 |
| Germany Bundesliga I | 2020/11/29 17:00 | Mainz v TSG Hoffenheim | D | 1-1 |
| Germany Bundesliga I | 2020/05/30 13:30 | Mainz v TSG Hoffenheim | W | 0-1 |
| Germany Bundesliga I | 2019/11/24 17:00 | TSG Hoffenheim v Mainz | L | 1-5 |
| Germany Bundesliga I | 2019/05/18 13:30 | Mainz v TSG Hoffenheim | L | 4-2 |
| Germany Bundesliga I | 2018/12/23 17:00 | TSG Hoffenheim v Mainz | D | 1-1 |
| Germany Bundesliga I | 2018/02/10 14:30 | TSG Hoffenheim v Mainz | W | 4-2 |
| Germany Bundesliga I | 2017/09/20 18:30 | Mainz v TSG Hoffenheim | W | 2-3 |
Home History
| Germany Bundesliga I | 2021/08/27 18:30 | Borussia Dortmund v TSG Hoffenheim | L | 3-2 |
| Germany Bundesliga I | 2021/08/22 13:30 | TSG Hoffenheim v Union Berlin | D | 2-2 |
| Germany Bundesliga I | 2021/08/14 13:30 | Augsburg v TSG Hoffenheim | W | 0-4 |
| Germany DFB Pokal | 2021/08/09 16:30 | FC Viktoria Köln v TSG Hoffenheim | W | 2-3 |
| Elite Club Friendlies | 2021/07/31 13:30 | TSG Hoffenheim v Reims | W | 3-1 |
| World Club Friendlies | 2021/07/24 12:00 | TSG Hoffenheim v Greuther Furth | D | 2-2 |
| Europe Friendlies | 2021/07/17 11:30 | Heidenheim v TSG Hoffenheim | L | 1-0 |
| Germany Bundesliga I | 2021/05/22 13:30 | TSG Hoffenheim v Hertha Berlin | W | 2-1 |
Away History
| Europe Friendlies | 2021/09/02 11:00 | Mainz v Karlsruher SC | D | 0-0 |
| Germany Bundesliga I | 2021/08/28 13:30 | Mainz v Greuther Furth | W | 3-0 |
| Germany Bundesliga I | 2021/08/21 13:30 | Bochum v Mainz | L | 2-0 |
| Germany Bundesliga I | 2021/08/15 13:30 | Mainz v RB Leipzig | W | 1-0 |
| Germany DFB Pokal | 2021/08/08 13:30 | Elversberg v Mainz | W | 9-10 |
| Elite Club Friendlies | 2021/07/31 15:30 | Mainz v Genoa | W | 3-2 |
| Europe Friendlies | 2021/07/27 16:00 | Mainz v Gazisehir Gaziantep FK | W | 1-0 |
| Elite Club Friendlies | 2021/07/23 16:15 | Liverpool v Mainz | L | 1-0 |