[9] Mainz 3-2 Bayer Leverkusen [3] 2022-02-18 19:30
Stadium: Mewa Arena Round: 23
Referee: Benjamin Cortus Home Manager: Bo Svensson Away Manager: Gerardo Seoane
Head to Head
| Germany Bundesliga I | 2021/09/25 13:30 | Bayer Leverkusen v Mainz | L | 1-0 |
| Germany Bundesliga I | 2021/02/13 14:30 | Bayer Leverkusen v Mainz | D | 2-2 |
| Germany Bundesliga I | 2020/10/17 13:30 | Mainz v Bayer Leverkusen | L | 0-1 |
| Germany Bundesliga I | 2020/06/27 13:30 | Bayer Leverkusen v Mainz | L | 1-0 |
| Germany Bundesliga I | 2019/12/21 14:30 | Mainz v Bayer Leverkusen | L | 0-1 |
| Germany Bundesliga I | 2019/02/08 19:30 | Mainz v Bayer Leverkusen | L | 1-5 |
| Germany Bundesliga I | 2018/09/23 13:30 | Bayer Leverkusen v Mainz | L | 1-0 |
| Germany Bundesliga I | 2018/01/28 14:30 | Bayer Leverkusen v Mainz | L | 2-0 |
Home History
| Germany Bundesliga I | 2022/02/12 14:30 | SC Freiburg v Mainz | D | 1-1 |
| Germany Bundesliga I | 2022/02/05 14:30 | Mainz v TSG Hoffenheim | W | 2-0 |
| Elite Club Friendlies | 2022/01/27 13:00 | Mainz v Eintracht Frankfurt | L | 0-1 |
| Germany Bundesliga I | 2022/01/22 14:30 | Greuther Furth v Mainz | L | 2-1 |
| Germany DFB Pokal | 2022/01/18 19:45 | Bochum v Mainz | L | 3-1 |
| Germany Bundesliga I | 2022/01/15 14:30 | Mainz v Bochum | W | 1-0 |
| Germany Bundesliga I | 2022/01/08 14:30 | RB Leipzig v Mainz | L | 4-1 |
| Germany Bundesliga I | 2021/12/18 14:30 | Eintracht Frankfurt v Mainz | L | 1-0 |
Away History
| Germany Bundesliga I | 2022/02/12 17:30 | Bayer Leverkusen v VfB Stuttgart | W | 4-2 |
| Germany Bundesliga I | 2022/02/06 14:30 | Borussia Dortmund v Bayer Leverkusen | W | 2-5 |
| Germany Bundesliga I | 2022/01/22 14:30 | Bayer Leverkusen v Augsburg | W | 5-1 |
| Germany Bundesliga I | 2022/01/15 17:30 | Borussia M'gladbach v Bayer Leverkusen | W | 1-2 |
| Germany Bundesliga I | 2022/01/08 14:30 | Bayer Leverkusen v Union Berlin | D | 2-2 |
| Germany Bundesliga I | 2021/12/19 14:30 | SC Freiburg v Bayer Leverkusen | L | 2-1 |
| Germany Bundesliga I | 2021/12/15 19:30 | Bayer Leverkusen v TSG Hoffenheim | D | 2-2 |
| Germany Bundesliga I | 2021/12/12 16:30 | Eintracht Frankfurt v Bayer Leverkusen | L | 5-2 |