[24] San Lorenzo 3-2 Newell's [19] 2021-12-12 20:00
Stadium: Estadio Pedro Bidegain Round: 25
Referee: Fernando Espinoza Home Manager: Diego Monarriz Away Manager: Adrian Blas Taffarel
Head to Head
| Argentina Superliga | 2020/02/04 00:10 | Newell's v San Lorenzo | L | 1-0 |
| Argentina Superliga | 2019/02/16 20:10 | San Lorenzo v Newell's | D | 1-1 |
| Argentina Superliga | 2018/02/17 20:00 | San Lorenzo v Newell's | W | 1-0 |
| Argentina Superliga | 2016/10/30 19:00 | Newell's v San Lorenzo | D | 2-2 |
| Argentina Liga Profesional | 2015/05/09 23:15 | Newell's v San Lorenzo | D | 1-1 |
| Argentina Liga Profesional | 2014/11/10 23:30 | Newell's v San Lorenzo | L | 3-1 |
Home History
| Argentina Liga Profesional | 2021/12/05 22:15 | CA Independiente v San Lorenzo | D | 1-1 |
| Argentina Liga Profesional | 2021/11/30 20:00 | San Lorenzo v Sarmiento | W | 1-0 |
| Argentina Liga Profesional | 2021/11/23 22:15 | CA Aldosivi v San Lorenzo | L | 2-0 |
| Argentina Liga Profesional | 2021/11/19 22:15 | San Lorenzo v Gimnasia LP | L | 0-1 |
| Argentina Liga Profesional | 2021/11/07 21:00 | Velez Sarsfield v San Lorenzo | L | 2-1 |
| Argentina Liga Profesional | 2021/10/31 18:45 | San Lorenzo v Godoy Cruz | W | 1-0 |
| Argentina Liga Profesional | 2021/10/24 21:00 | Huracan v San Lorenzo | L | 2-1 |
| Argentina Liga Profesional | 2021/10/20 19:45 | San Lorenzo v Lanus | L | 1-3 |
Away History
| Argentina Liga Profesional | 2021/12/07 00:30 | Newell's v Banfield | D | 0-0 |
| Argentina Liga Profesional | 2021/11/30 22:15 | Boca Juniors v Newell's | D | 0-0 |
| Argentina Liga Profesional | 2021/11/24 20:00 | Newell's v Central Cordoba | W | 1-0 |
| Argentina Liga Profesional | 2021/11/21 20:00 | Arsenal de Sarandi v Newell's | L | 3-1 |
| Argentina Liga Profesional | 2021/11/08 19:45 | Newell's v Union Santa Fe | W | 1-0 |
| Argentina Liga Profesional | 2021/10/31 21:00 | Newell's v CA Independiente | W | 1-0 |
| Argentina Liga Profesional | 2021/10/25 17:30 | Sarmiento v Newell's | L | 2-1 |
| Argentina Liga Profesional | 2021/10/21 19:45 | Newell's v CA Aldosivi | D | 0-0 |