[5] Real Betis 0-2 Sevilla [3] 2021-11-07 20:00
Stadium: Benito Villamarin Round: 13
Referee: Antonio Miguel Mateu Lahoz Home Manager: Manuel Pellegrini Away Manager: Julen Lopetegui
Head to Head
| Spain La Liga | 2021/03/14 20:00 | Sevilla v Real Betis | L | 1-0 |
| Spain La Liga | 2021/01/02 15:15 | Real Betis v Sevilla | D | 1-1 |
| Spain La Liga | 2020/06/11 20:00 | Sevilla v Real Betis | L | 2-0 |
| Spain La Liga | 2019/11/10 20:00 | Real Betis v Sevilla | L | 1-2 |
| Spain La Liga | 2019/04/13 18:45 | Sevilla v Real Betis | L | 3-2 |
| Spain La Liga | 2018/09/02 18:45 | Real Betis v Sevilla | W | 1-0 |
| Spain La Liga | 2018/05/12 16:30 | Real Betis v Sevilla | D | 2-2 |
| Spain La Liga | 2018/01/06 19:45 | Sevilla v Real Betis | W | 3-5 |
Home History
| UEFA Europa League | 2021/11/04 20:00 | Bayer Leverkusen v Real Betis | L | 4-0 |
| Spain La Liga | 2021/10/31 15:15 | Atletico Madrid v Real Betis | L | 3-0 |
| Spain La Liga | 2021/10/27 18:00 | Real Betis v Valencia | W | 4-1 |
| Spain La Liga | 2021/10/24 16:30 | Real Betis v Rayo Vallecano | W | 3-2 |
| UEFA Europa League | 2021/10/21 16:45 | Real Betis v Bayer Leverkusen | D | 1-1 |
| Spain La Liga | 2021/10/18 17:00 | CD Alaves v Real Betis | W | 0-1 |
| Spain La Liga | 2021/10/03 16:30 | Villarreal v Real Betis | L | 2-0 |
| UEFA Europa League | 2021/09/30 19:00 | Ferencvarosi TC v Real Betis | W | 1-3 |
Away History
| UEFA Champions League | 2021/11/02 20:00 | Sevilla v Lille | L | 1-2 |
| Spain La Liga | 2021/10/30 14:15 | Sevilla v Osasuna | W | 2-0 |
| Spain La Liga | 2021/10/27 17:00 | Mallorca v Sevilla | D | 1-1 |
| Spain La Liga | 2021/10/24 12:00 | Sevilla v Levante | W | 5-3 |
| UEFA Champions League | 2021/10/20 19:00 | Lille v Sevilla | D | 0-0 |
| Spain La Liga | 2021/10/17 14:15 | Celta Vigo v Sevilla | W | 0-1 |
| Spain La Liga | 2021/10/03 19:00 | Granada v Sevilla | L | 1-0 |
| UEFA Champions League | 2021/09/29 19:00 | Wolfsburg v Sevilla | D | 1-1 |