Head to Head
| Netherlands Eredivisie | 2021/04/03 18:00 | FC Twente v Vitesse | W | 1-2 |
| Netherlands Eredivisie | 2021/02/14 15:45 | Vitesse v FC Twente | L | 0-2 |
| Netherlands Eredivisie | 2020/03/07 18:45 | Vitesse v FC Twente | W | 1-0 |
| Netherlands Eredivisie | 2019/12/14 19:45 | FC Twente v Vitesse | W | 0-3 |
| Netherlands Eredivisie | 2018/04/29 12:30 | Vitesse v FC Twente | W | 5-0 |
| Netherlands Eredivisie | 2017/12/16 19:45 | FC Twente v Vitesse | D | 1-1 |
| Netherlands Eredivisie | 2017/01/15 13:30 | Vitesse v FC Twente | W | 3-1 |
| Netherlands Eredivisie | 2016/09/25 12:30 | FC Twente v Vitesse | L | 2-1 |
Home History
| UEFA Conference League | 2021/09/16 16:45 | NS Mura v Vitesse | W | 0-2 |
| Netherlands Eredivisie | 2021/09/12 14:45 | RKC v Vitesse | W | 1-2 |
| Netherlands Eredivisie | 2021/08/29 12:30 | Ajax v Vitesse | L | 5-0 |
| UEFA Conference League Qualifying | 2021/08/26 17:00 | Vitesse v Anderlecht | W | 2-1 |
| Netherlands Eredivisie | 2021/08/22 14:45 | Vitesse v Willem II | L | 0-3 |
| UEFA Conference League Qualifying | 2021/08/19 18:00 | Anderlecht v Vitesse | D | 3-3 |
| Netherlands Eredivisie | 2021/08/15 12:30 | PEC Zwolle v Vitesse | W | 0-1 |
| UEFA Conference League Qualifying | 2021/08/12 19:00 | Dundalk v Vitesse | W | 1-2 |
Away History
| Netherlands Eredivisie | 2021/09/11 14:30 | FC Twente v FC Utrecht | W | 1-0 |
| Netherlands Eredivisie | 2021/08/28 16:45 | Cambuur Leeuwarden v FC Twente | L | 2-0 |
| Netherlands Eredivisie | 2021/08/22 10:15 | FC Twente v Ajax | D | 1-1 |
| Netherlands Eredivisie | 2021/08/14 18:00 | Fortuna Sittard v FC Twente | L | 2-1 |
| Europe Friendlies | 2021/08/07 17:30 | FC Twente v Lazio | L | 0-1 |
| Europe Friendlies | 2021/08/03 13:00 | FC Twente v Venezia | L | 0-1 |
| Europe Friendlies | 2021/07/31 13:30 | Arminia Bielefeld v FC Twente | D | 1-1 |
| Netherlands Eredivisie | 2021/05/16 12:30 | FC Twente v ADO Den Haag | W | 3-2 |