[2] Leon 1-1 Santos Laguna [9] 2021-08-22 00:00
Stadium: Estadio Leon Round: 6
Referee: Fernando Hernandez Gomez Home Manager: Ariel Holan Away Manager: Guillermo Almada
Head to Head
| Mexico Liga MX | 2021/03/22 01:06 | Santos Laguna v Leon | W | 1-2 |
| Mexico Liga MX | 2020/11/03 03:00 | Leon v Santos Laguna | W | 2-1 |
| Mexico Liga MX | 2020/01/20 00:45 | Santos Laguna v Leon | L | 3-2 |
| Mexico Liga MX | 2019/08/29 00:00 | Leon v Santos Laguna | D | 2-2 |
| Mexico Liga MX | 2019/03/03 01:00 | Leon v Santos Laguna | W | 3-0 |
| Mexico Liga MX | 2018/09/16 21:00 | Santos Laguna v Leon | L | 3-0 |
| Mexico Liga MX | 2018/02/15 01:00 | Santos Laguna v Leon | L | 5-1 |
| Mexico Liga MX | 2017/08/27 00:06 | Leon v Santos Laguna | L | 1-2 |
Home History
| Mexico Liga MX | 2021/08/19 02:00 | Chivas Guadalajara v Leon | W | 0-3 |
| Mexico Liga MX | 2021/08/15 00:00 | Leon v Mazatlan FC | W | 3-0 |
| Leagues Cup | 2021/08/11 00:00 | Sporting Kansas City v Leon | W | 1-6 |
| Mexico Liga MX | 2021/08/06 02:05 | Queretaro v Leon | W | 0-1 |
| Mexico Liga MX | 2021/07/31 22:00 | Leon v Tijuana | W | 2-1 |
| Mexico Liga MX | 2021/07/24 21:00 | Pachuca v Leon | L | 4-0 |
| Mexico Champion of Champions | 2021/07/18 23:30 | Leon v Cruz Azul | L | 1-2 |
| Mexico Liga MX | 2021/05/10 00:00 | Leon v Toluca | L | 4-6 |
Away History
| Mexico Liga MX | 2021/08/19 00:00 | Santos Laguna v Atlas | D | 1-1 |
| Mexico Liga MX | 2021/08/16 00:06 | Santos Laguna v Chivas Guadalajara | D | 0-0 |
| Leagues Cup | 2021/08/12 23:00 | Orlando City SC v Santos Laguna | W | 0-1 |
| Mexico Liga MX | 2021/08/08 02:00 | Tigres UANL v Santos Laguna | D | 1-1 |
| Mexico Liga MX | 2021/08/01 23:00 | Santos Laguna v Cruz Azul | D | 1-1 |
| Mexico Liga MX | 2021/07/24 00:00 | Necaxa v Santos Laguna | W | 0-3 |
| Club Friendly List | 2021/07/05 00:30 | Club America v Santos Laguna | L | 1-0 |
| Mexico Liga MX | 2021/05/31 01:15 | Cruz Azul v Santos Laguna | D | 1-1 |