| Australia Victoria U21 League | 2021/04/10 06:30 | Hume City U21 v Port Melbourne U21 | L | 3-2 |
| Australia Victoria U21 League | 2021/07/04 02:30 | St Albans Saints U21 v Port Melbourne U21 | L | 4-1 |
| Australia Victoria U21 League | 2021/06/26 05:00 | Port Melbourne U21 v Dandenong Thunder U21 | D | 1-1 |
| Australia Victoria U21 League | 2021/06/19 02:30 | South Melbourne U21 v Port Melbourne U21 | L | 6-1 |
| Australia Victoria U21 League | 2021/05/21 08:30 | Dandenong City U21 v Port Melbourne U21 | W | 0-2 |
| Australia Victoria U21 League | 2021/05/15 05:00 | Port Melbourne U21 v Green Gully U21 | W | 3-2 |
| Australia Victoria U21 League | 2021/05/08 06:30 | Altona Magic U21 v Port Melbourne U21 | D | 2-2 |
| Australia Victoria U21 League | 2021/05/01 03:00 | Port Melbourne U21 v Oakleigh Cannons U21 | L | 1-2 |
| Australia Victoria U21 League | 2021/04/24 03:00 | Heidelberg Utd U21 v Port Melbourne U21 | W | 1-2 |
| Australia Victoria U21 League | 2021/07/03 09:45 | Hume City U21 v Eastern Lions U21 | L | 1-2 |
| Australia Victoria U21 League | 2021/06/25 08:15 | Bentleigh Greens U21 v Hume City U21 | L | 1-0 |
| Australia Victoria U21 League | 2021/06/19 09:45 | Hume City U21 v Melbourne Knights U21 | L | 0-1 |
| Australia Victoria U21 League | 2021/05/21 08:15 | Oakleigh Cannons U21 v Hume City U21 | W | 1-2 |
| Australia Victoria U21 League | 2021/05/15 09:45 | Hume City U21 v Heidelberg Utd U21 | D | 0-0 |
| Australia Victoria U21 League | 2021/05/08 02:15 | Avondale U21 v Hume City U21 | D | 1-1 |
| Australia Victoria U21 League | 2021/05/01 07:15 | South Melbourne U21 v Hume City U21 | D | 2-2 |
| Australia Victoria U21 League | 2021/04/24 09:45 | Hume City U21 v St Albans Saints U21 | D | 1-1 |