[16] Southampton 1-1 Man Utd [6] 2021-08-22 13:00
Stadium: St. Mary's Stadium Round: 2
Referee: Craig Pawson Home Manager: Ralph Hasenhuttl Away Manager: Ole Gunnar Solskjaer
Head to Head
| England Premier League | 2021/02/02 20:15 | Man Utd v Southampton | L | 9-0 |
| England Premier League | 2020/11/29 14:00 | Southampton v Man Utd | L | 2-3 |
| England Premier League | 2020/07/13 19:00 | Man Utd v Southampton | D | 2-2 |
| England Premier League | 2019/08/31 11:30 | Southampton v Man Utd | D | 1-1 |
| England Premier League | 2019/03/02 15:00 | Man Utd v Southampton | L | 3-2 |
| England Premier League | 2018/12/01 17:30 | Southampton v Man Utd | D | 2-2 |
| England Premier League | 2017/12/30 17:30 | Man Utd v Southampton | D | 0-0 |
| England Premier League | 2017/09/23 14:00 | Southampton v Man Utd | L | 0-1 |
Home History
| England Premier League | 2021/08/14 14:00 | Everton v Southampton | L | 3-1 |
| Elite Club Friendlies | 2021/08/07 14:00 | Southampton v Athletic Bilbao | L | 1-3 |
| Elite Club Friendlies | 2021/08/04 18:00 | Southampton v Levante | W | 1-0 |
| Elite Club Friendlies | 2021/07/31 14:00 | Swansea v Southampton | W | 1-3 |
| Elite Club Friendlies | 2021/07/27 18:00 | Cardiff v Southampton | W | 0-4 |
| England Premier League | 2021/05/23 15:00 | West Ham v Southampton | L | 3-0 |
| England Premier League | 2021/05/18 17:00 | Southampton v Leeds | L | 0-2 |
| England Premier League | 2021/05/15 14:00 | Southampton v Fulham | W | 3-1 |
Away History
| England Premier League | 2021/08/14 11:30 | Man Utd v Leeds | W | 5-1 |
| Elite Club Friendlies | 2021/08/07 11:45 | Man Utd v Everton | W | 4-0 |
| Elite Club Friendlies | 2021/07/28 19:00 | Man Utd v Brentford | D | 2-2 |
| Elite Club Friendlies | 2021/07/24 14:00 | QPR v Man Utd | L | 4-2 |
| Elite Club Friendlies | 2021/07/18 12:00 | Derby v Man Utd | W | 1-2 |
| UEFA Europa League | 2021/05/26 19:00 | Villarreal v Man Utd | L | 12-11 |
| England Premier League | 2021/05/23 15:00 | Wolverhampton v Man Utd | W | 1-2 |
| England Premier League | 2021/05/18 17:00 | Man Utd v Fulham | D | 1-1 |