[14] Southampton 1-0 Aston Villa [15] 2021-11-05 20:00
Stadium: St. Mary's Stadium Round: 11
Referee: Andrew Madley Home Manager: Ralph Hasenhuttl Away Manager: Dean Smith
Head to Head
| England Premier League | 2021/01/30 20:00 | Southampton v Aston Villa | L | 0-1 |
| England Premier League | 2020/11/01 12:00 | Aston Villa v Southampton | W | 3-4 |
| England Premier League | 2020/02/22 15:00 | Southampton v Aston Villa | W | 2-0 |
| England Premier League | 2019/12/21 15:00 | Aston Villa v Southampton | W | 1-3 |
| England Premier League | 2016/04/23 14:00 | Aston Villa v Southampton | W | 2-4 |
| England Premier League | 2015/12/05 15:00 | Southampton v Aston Villa | D | 1-1 |
| England EFL Cup | 2015/10/28 19:45 | Southampton v Aston Villa | W | 2-1 |
| England Premier League | 2015/05/16 11:45 | Southampton v Aston Villa | W | 6-1 |
Home History
| England Premier League | 2021/10/30 14:00 | Watford v Southampton | W | 0-1 |
| England EFL Cup | 2021/10/26 18:45 | Chelsea v Southampton | L | 5-4 |
| England Premier League | 2021/10/23 14:00 | Southampton v Burnley | D | 2-2 |
| England Premier League | 2021/10/16 14:00 | Southampton v Leeds | W | 1-0 |
| England Premier League | 2021/10/02 14:00 | Chelsea v Southampton | L | 3-1 |
| England Premier League | 2021/09/26 13:00 | Southampton v Wolverhampton | L | 0-1 |
| England EFL Cup | 2021/09/21 18:45 | Sheff Utd v Southampton | W | 4-6 |
| England Premier League | 2021/09/18 14:00 | Man City v Southampton | D | 0-0 |
Away History
| England Premier League | 2021/10/31 16:30 | Aston Villa v West Ham | L | 1-4 |
| England Premier League | 2021/10/22 19:00 | Arsenal v Aston Villa | L | 3-1 |
| England Premier League | 2021/10/16 14:00 | Aston Villa v Wolverhampton | L | 2-3 |
| England Premier League | 2021/10/03 13:00 | Tottenham v Aston Villa | L | 2-1 |
| England Premier League | 2021/09/25 11:30 | Man Utd v Aston Villa | W | 0-1 |
| England EFL Cup | 2021/09/22 18:45 | Chelsea v Aston Villa | L | 5-4 |
| England Premier League | 2021/09/18 16:30 | Aston Villa v Everton | W | 3-0 |
| England Premier League | 2021/09/11 16:30 | Chelsea v Aston Villa | L | 3-0 |