[6] Cologne II 0-3 Wuppertaler [4] 2021-11-05 18:00
Stadium: Franz-Kremer-Stadion Round: 15
Referee: Leonidas Exuzidis Home Manager: Mark Zimmermann Away Manager: Bjorn Mehnert
Head to Head
| Germany Regionalliga West | 2021/04/17 13:30 | Wuppertaler v Cologne II | L | 2-0 |
| Germany Regionalliga West | 2020/11/14 13:00 | Cologne II v Wuppertaler | W | 1-0 |
| Germany Regionalliga West | 2019/08/23 17:30 | Wuppertaler v Cologne II | W | 0-1 |
| Germany Regionalliga West | 2019/05/19 12:00 | Wuppertaler v Cologne II | W | 2-4 |
| Germany Regionalliga West | 2018/11/10 12:00 | Cologne II v Wuppertaler | D | 1-1 |
| Germany Regionalliga West | 2018/05/13 12:00 | Wuppertaler v Cologne II | L | 3-1 |
| Germany Regionalliga West | 2017/10/25 17:30 | Cologne II v Wuppertaler | W | 6-3 |
| Germany Regionalliga West | 2017/04/01 12:00 | Wuppertaler v Cologne II | W | 1-3 |
Home History
| Germany Regionalliga West | 2021/10/30 12:00 | SV Straelen v Cologne II | W | 1-2 |
| Germany Regionalliga West | 2021/10/27 12:00 | Cologne II v SV Rodinghausen | L | 2-3 |
| Germany Regionalliga West | 2021/10/23 12:00 | Cologne II v Rot-Weiss Essen | D | 1-1 |
| Germany Regionalliga West | 2021/10/15 17:00 | Rot Weiss Ahlen v Cologne II | W | 2-6 |
| Germany Regionalliga West | 2021/10/01 17:00 | FC Wegberg-Beeck v Cologne II | W | 0-1 |
| Germany Regionalliga West | 2021/09/28 17:30 | SC Wiedenbruck v Cologne II | L | 2-0 |
| Germany Regionalliga West | 2021/09/25 12:00 | Cologne II v Sportfreunde Lotte | W | 4-0 |
| Germany Regionalliga West | 2021/09/18 12:00 | Borussia M'gladbach II v Cologne II | L | 3-1 |
Away History
| Germany Regionalliga West | 2021/10/30 12:00 | Wuppertaler v SC Wiedenbruck | D | 0-0 |
| Germany Regionalliga West | 2021/10/23 12:00 | KFC Uerdingen 05 v Wuppertaler | W | 0-2 |
| Germany Regionalliga West | 2021/10/16 12:00 | Wuppertaler v Rot-Weiss Oberhausen | D | 1-1 |
| Germany Landespokal | 2021/10/12 17:00 | Wuppertaler v SC Werden Heidhausen | W | 4-0 |
| Germany Regionalliga West | 2021/10/08 16:00 | SV Lippstadt 08 v Wuppertaler | D | 2-2 |
| Germany Regionalliga West | 2021/10/02 12:00 | Wuppertaler v Schalke II | W | 3-0 |
| Germany Landespokal | 2021/09/29 17:30 | Wuppertaler v VfL Viktoria Juchen-Garzweiler | W | 2-0 |
| Germany Regionalliga West | 2021/09/26 12:00 | SC Preussen Munster v Wuppertaler | D | 0-0 |