[1] Northampton 7-5 Southampton U21 [3] 2017-11-07 19:45
Weather: Rainy Stadium: Sixfields Stadium Pitch: Wet and Fast Round: 3
Home History
| England FA Cup | 2017/11/04 15:00 | Northampton v Scunthorpe | D | 0-0 |
| England League 1 | 2017/10/28 13:00 | Northampton v Blackpool | W | 1-0 |
| England League 1 | 2017/10/21 14:00 | Gillingham v Northampton | W | 1-2 |
| England League 1 | 2017/10/17 18:45 | Rochdale v Northampton | D | 2-2 |
| England League 1 | 2017/10/14 14:00 | Northampton v AFC Wimbledon | L | 0-1 |
| England League 1 | 2017/10/07 14:00 | Northampton v Bristol Rovers | L | 0-6 |
| England EFL Trophy | 2017/10/03 18:45 | Peterborough v Northampton | W | 3-5 |
| England League 1 | 2017/09/30 14:00 | Rotherham v Northampton | L | 1-0 |
Away History
| England EFL Trophy | 2017/10/03 18:00 | Cambridge Utd v Southampton U21 | W | 0-1 |
| England EFL Trophy | 2017/08/29 18:45 | Peterborough v Southampton U21 | L | 2-0 |
| England Premier League 2 | 2017/08/14 18:00 | Southampton U21 v Reading U21 | W | 4-0 |
| England Premier League 2 | 2016/09/19 18:00 | Southampton U21 v Leicester U21 | D | 2-2 |
| England EFL Trophy | 2016/08/30 18:45 | Charlton v Southampton U21 | L | 5-4 |
| England Premier League 2 | 2016/08/22 18:00 | Southampton U21 v Man Utd U21 | W | 2-0 |
| England Premier League 2 | 2016/08/14 12:00 | Liverpool U21 v Southampton U21 | W | 1-4 |
| England U21 Premier League Cup | 2015/04/20 18:00 | Southampton U21 v Blackburn U21 | W | 2-1 |