Head to Head
| Mexico U20 League | 2021/05/02 16:00 | Santos Laguna U20 v Puebla U20 | L | 2-3 |
| Mexico U20 League | 2020/10/02 14:00 | Puebla U20 v Santos Laguna U20 | L | 2-1 |
| Mexico U20 League | 2020/02/07 18:00 | Puebla U20 v Santos Laguna U20 | W | 1-3 |
| Mexico U20 League | 2019/08/11 16:00 | Santos Laguna U20 v Puebla U20 | W | 5-2 |
| Mexico U20 League | 2019/01/18 18:00 | Puebla U20 v Santos Laguna U20 | D | 1-1 |
| Mexico U20 League | 2018/09/08 16:30 | Santos Laguna U20 v Puebla U20 | L | 2-3 |
| Mexico U20 League | 2018/03/16 18:00 | Puebla U20 v Santos Laguna U20 | L | 3-1 |
| Mexico U20 League | 2017/10/01 16:00 | Santos Laguna U20 v Puebla U20 | W | 2-1 |
Home History
| Mexico U20 League | 2021/09/15 14:00 | Club America U20 v Santos Laguna U20 | W | 0-1 |
| Mexico U20 League | 2021/09/10 22:45 | Tijuana U20 v Santos Laguna U20 | D | 2-2 |
| Mexico U20 League | 2021/08/29 16:00 | Santos Laguna U20 v FC Juarez U20 | W | 3-1 |
| Mexico U20 League | 2021/08/21 14:00 | Leon U20 v Santos Laguna U20 | D | 1-1 |
| Mexico U20 League | 2021/08/18 16:00 | Santos Laguna U20 v Atlas U20 | W | 3-1 |
| Mexico U20 League | 2021/08/15 16:00 | Santos Laguna U20 v Chivas Guadalajara U20 | L | 1-2 |
| Mexico U20 League | 2021/08/07 14:00 | Tigres U20 v Santos Laguna U20 | D | 1-1 |
| Mexico U20 League | 2021/08/01 16:00 | Santos Laguna U20 v Cruz Azul U20 | W | 1-0 |
Away History
| Mexico U20 League | 2021/09/10 14:00 | Puebla U20 v Atletico San Luis U20 | D | 2-2 |
| Mexico U20 League | 2021/08/27 14:00 | Puebla U20 v Queretaro U20 | L | 0-1 |
| Mexico U20 League | 2021/08/22 14:00 | Unam Pumas U20 v Puebla U20 | W | 1-3 |
| Mexico U20 League | 2021/08/17 22:45 | Tijuana U20 v Puebla U20 | L | 3-0 |
| Mexico U20 League | 2021/08/13 14:00 | Puebla U20 v Tigres U20 | W | 2-1 |
| Mexico U20 League | 2021/08/07 14:00 | Club America U20 v Puebla U20 | D | 3-3 |
| Mexico U20 League | 2021/07/30 14:00 | Puebla U20 v Chivas Guadalajara U20 | W | 3-1 |
| Mexico U20 League | 2021/07/24 14:00 | Monterrey U20 v Puebla U20 | L | 4-1 |